Ruthenium(ii) polypyridyl complexes as dual inhibitors of telomerase and topoisomerase

Dalton Transactions ◽

10.1039/c4dt03585b ◽

2015 ◽

Vol 44 (34) ◽

pp. 15145-15156 ◽

Author(s):

Guoliang Liao ◽

Xiang Chen ◽

Jingheng Wu ◽

Chen Qian ◽

Yi Wang ◽

...

Keyword(s):

Topoisomerase I ◽

Polypyridyl Complexes ◽

Quadruplex Structure ◽

G Quadruplex ◽

Dual Inhibitors

Three ruthenium(ii) polypyridyl complexes, [Ru(bpy)2(icip)]2+ (1), [Ru(bpy)2(pdppz)]2+ (2), and [Ru(bpy)2(tactp)]2+ (3), were selected to inhibit telomerase by inducing and stabilising the G-quadruplex structure, and behave as topoisomerase I/II poisons at the same time.

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First Tandem Repeat of a Potassium Channel KCNN4 Minisatellite Folds into a V-Loop G-Quadruplex Structure

Biochemistry ◽

10.1021/acs.biochem.1c00043 ◽

2021 ◽

Author(s):

Yoanes Maria Vianney ◽

Klaus Weisz

Keyword(s):

Potassium Channel ◽

Tandem Repeat ◽

Quadruplex Structure ◽

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Radical cation transfer in a guanine pair: an insight to the G-quadruplex structure role using constrained DFT/MM

Theoretical Chemistry Accounts ◽

10.1007/s00214-021-02787-0 ◽

2021 ◽

Vol 140 (7) ◽

Author(s):

Ranjitha Ravindranath ◽

Padmabati Mondal ◽

Natacha Gillet

Keyword(s):

Radical Cation ◽

Quadruplex Structure ◽

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Investigation on the formation, conversion and bioactivity of a G-quadruplex structure in the PALB2 gene

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2015.11.069 ◽

2016 ◽

Vol 83 ◽

pp. 242-248 ◽

Author(s):

Fangyuan Li ◽

Jiang Zhou ◽

Ming Xu ◽

Gu Yuan

Keyword(s):

Quadruplex Structure ◽

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Fully integrated graphene electronic biosensor for label-free detection of lead (II) ion based on G-quadruplex structure-switching

Biosensors and Bioelectronics ◽

10.1016/j.bios.2016.10.061 ◽

2017 ◽

Vol 89 ◽

pp. 758-763 ◽

Author(s):

Yijun Li ◽

Cheng Wang ◽

Yibo Zhu ◽

Xiaohong Zhou ◽

Yu Xiang ◽

...

Keyword(s):

Fully Integrated ◽

Quadruplex Structure ◽

Label Free Detection ◽

G Quadruplex ◽

Structure Switching

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Design and Synthesis of an Expanded Porphyrin That Has Selectivity for the c-MYC G-Quadruplex Structure

Journal of the American Chemical Society ◽

10.1021/ja0444482 ◽

2005 ◽

Vol 127 (9) ◽

pp. 2944-2959 ◽

Author(s):

Jeyaprakashnarayanan Seenisamy ◽

Sridevi Bashyam ◽

Vijay Gokhale ◽

Hariprasad Vankayalapati ◽

Daekyu Sun ◽

...

Keyword(s):

Design And Synthesis ◽

Quadruplex Structure ◽

G Quadruplex ◽

Expanded Porphyrin

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Novel ruthenium(ii) polypyridyl complexes as G-quadruplex stabilisers and telomerase inhibitors

Dalton Transactions ◽

10.1039/c3dt53547a ◽

2014 ◽

Vol 43 (21) ◽

pp. 7811 ◽

Author(s):

Guoliang Liao ◽

Xiang Chen ◽

Jingheng Wu ◽

Chen Qian ◽

Hanqiang Wang ◽

...

Keyword(s):

Polypyridyl Complexes ◽

Telomerase Inhibitors ◽

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Up- and downregulation of mature miR-1587 function by modulating its G-quadruplex structure and using small molecules

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2018.10.017 ◽

2019 ◽

Vol 121 ◽

pp. 127-134 ◽

Author(s):

Fangyuan Li ◽

Wei Tan ◽

Han Chen ◽

Jiang Zhou ◽

Ming Xu ◽

...

Keyword(s):

Small Molecules ◽

Quadruplex Structure ◽

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Specific Binding of a d ‐RNA G‐Quadruplex Structure with an l ‐RNA Aptamer

Angewandte Chemie ◽

10.1002/ange.201914955 ◽

2020 ◽

Vol 132 (13) ◽

pp. 5331-5335

Author(s):

Chun‐Yin Chan ◽

Chun Kit Kwok

Keyword(s):

Specific Binding ◽

Rna Aptamer ◽

Quadruplex Structure ◽

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Effect of G-quadruplex structure on the peroxidase-like DNAzyme activity

Clinical Biochemistry ◽

10.1016/j.clinbiochem.2011.08.215 ◽

2011 ◽

Vol 44 (13) ◽

pp. S94-S95

Author(s):

Zahra Karami ◽

Bijan Ranjbar ◽

Arastoo Badoei-Dalfard

Keyword(s):

Quadruplex Structure ◽

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Intermolecular G-quadruplex structure-based fluorescent DNA detection system

Biosensors and Bioelectronics ◽

10.1016/j.bios.2012.08.028 ◽

2013 ◽

Vol 41 ◽

pp. 262-267 ◽

Author(s):

Hui Zhou ◽

Zai-Sheng Wu ◽

Guo-Li Shen ◽

Ru-Qin Yu

Keyword(s):

Detection System ◽

Dna Detection ◽

Quadruplex Structure ◽

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