Iterative multitarget evolution dramatically enhances the enantioselectivity and catalytic efficiency of Bacillus subtilis esterase towards bulky benzoate esters of dl-menthol

2016 ◽  
Vol 6 (7) ◽  
pp. 2370-2376 ◽  
Author(s):  
Yi Gong ◽  
Guo-Chao Xu ◽  
Qi Chen ◽  
Jin-Gang Yin ◽  
Chun-Xiu Li ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Directed Evolution ◽  
Catalytic Efficiency

Structure-based directed evolution has been successfully applied to Bacillus subtilis esterase to produce a mutant with higher enantioselectivity and elevated efficiency.

Improved catalytic efficiency of Endo-β-1,4-glucanase from Bacillus subtilis BME-15 by directed evolution

2009 ◽  
Vol 82 (4) ◽  
pp. 671-679 ◽  
Author(s):  
Ling Lin ◽  
Xin Meng ◽  
Pengfu Liu ◽  
Yuzhi Hong ◽  
Gaobing Wu ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Directed Evolution ◽  
Catalytic Efficiency

scholarly journals Directed evolution to improve the catalytic efficiency of urate oxidase from Bacillus subtilis

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177877 ◽  
Author(s):  
Wenjie Li ◽  
Shouteng Xu ◽  
Biao Zhang ◽  
Yelin Zhu ◽  
Yan Hua ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Directed Evolution ◽  
Catalytic Efficiency ◽  
Urate Oxidase

scholarly journals Directed evolution of lipase A from Bacillus subtilis for the preparation of enantiocomplementary sec-alcohols

2021 ◽  
Author(s):  
Danyang Li ◽  
Xiaoyang Chen ◽  
Zhichun Chen ◽  
Xianfu Lin ◽  
Jian Xu ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Directed Evolution ◽  
Lipase A

Efficient secretory production of large‐size heterologous enzymes in Bacillus subtilis : A secretory partner and directed evolution

2020 ◽  
Vol 117 (10) ◽  
pp. 2957-2968
Author(s):  
Shan Liu ◽  
Juan Wang ◽  
Zhiguang Zhu ◽  
Ting Shi ◽  
Yi‐Heng P. Job Zhang
Keyword(s):  
Bacillus Subtilis ◽  
Directed Evolution ◽  
Large Size ◽  
Secretory Production

scholarly journals Directed evolution improves the catalytic efficiency of TEV protease

2019 ◽  
Vol 17 (2) ◽  
pp. 167-174 ◽  
Author(s):  
Mateo I. Sanchez ◽  
Alice Y. Ting
Keyword(s):  
Directed Evolution ◽  
Catalytic Efficiency ◽  
Tev Protease

Directed Evolution of Bacillus subtilis Lipase A by Use of Enantiomeric Phosphonate Inhibitors: Crystal Structures and Phage Display Selection

ChemBioChem ◽  
2005 ◽  
Vol 7 (1) ◽  
pp. 149-157 ◽  
Author(s):  
Melloney J. Dröge ◽  
Ykelien L. Boersma ◽  
Gertie van Pouderoyen ◽  
Titia E. Vrenken ◽  
Carsten J. Rüggeberg ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Phage Display ◽  
Directed Evolution ◽  
Crystal Structures ◽  
Lipase A
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