A simple strategy for signal amplification based on DNA hybridization chain reaction for thrombin detection

2015 ◽  
Vol 39 (9) ◽  
pp. 6965-6969 ◽  
Author(s):  
XiaoYing Liu ◽  
GuangYu Shen

Multiple enzymes were introduced onto the surface of electrode, which resulted in significant signal amplification.

2019 ◽  
Vol 43 (24) ◽  
pp. 9458-9465
Author(s):  
Xiquan Yue ◽  
Lihong Su ◽  
Xu Chen ◽  
Junfeng Liu ◽  
Longpo Zheng ◽  
...  

The strategy is based on small molecule-mediated hybridization chain reaction.


2012 ◽  
Vol 70 (20) ◽  
pp. 2127 ◽  
Author(s):  
Ping Wang ◽  
Zhilei Ge ◽  
Hao Pei ◽  
Lihua Wang ◽  
Chunhai Fan

2020 ◽  
Vol 8 (47) ◽  
pp. 10770-10775
Author(s):  
Chao Xing ◽  
Ziyi Chen ◽  
Cheng Zhang ◽  
Jun Wang ◽  
Chunhua Lu

An enzyme-free, single-step and rapid signal amplification DNA circuit was developed by integrating target-directed entropy-driven catalysis and hybridization chain reaction for fluorescence analysis of nucleic acids and small molecules.


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