Target-directed enzyme-free dual-amplification DNA circuit for rapid signal amplification

2020 ◽  
Vol 8 (47) ◽  
pp. 10770-10775
Author(s):  
Chao Xing ◽  
Ziyi Chen ◽  
Cheng Zhang ◽  
Jun Wang ◽  
Chunhua Lu

An enzyme-free, single-step and rapid signal amplification DNA circuit was developed by integrating target-directed entropy-driven catalysis and hybridization chain reaction for fluorescence analysis of nucleic acids and small molecules.

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