Catalyst-free, one-pot, four-component green synthesis of functionalized 1-(2-fluorophenyl)-1,4-dihydropyridines under ultrasound irradiation

2016 ◽  
Vol 40 (6) ◽  
pp. 5107-5112 ◽  
Author(s):  
Nhlanhla Shabalala ◽  
Suresh Maddila ◽  
Sreekantha B. Jonnalagadda

A catalyst-free synthesis protocol for functionalized 1,4-dihydropyridines under ultrasonic irradiation in aqueous ethanol is reported with excellent yields. Eleven new compounds are synthesized using dimethylacetylenedicarboxylate, 2-fluoroaniline, malononitrile and various substituted aldehydes.

2020 ◽  
Vol 50 (13) ◽  
pp. 1960-1971 ◽  
Author(s):  
Shabalala Nhlanhla Gracious ◽  
Nagaraju Kerru ◽  
Suresh Maddila ◽  
Werner E. van Zyl ◽  
Sreekantha B. Jonnalagadda

RSC Advances ◽  
2015 ◽  
Vol 5 (121) ◽  
pp. 99775-99780 ◽  
Author(s):  
Abdeslem Bouzina ◽  
Malika Berredjem ◽  
Sofiane Bouacida ◽  
Hocine Merazig ◽  
Nour-eddine Aouf

The synthesis of α-ureidophosphonates via a one-pot three-component reaction using ultrasonic irradiation under solvent- and catalyst-free conditions at 75° is developed. The products were obtained in excellent yields within short reaction times.


2020 ◽  
Vol 26 ◽  
pp. 100365 ◽  
Author(s):  
Nhlanhla Gracious Shabalala ◽  
Nagaraju Kerru ◽  
Suresh Maddila ◽  
Werner E. van Zyl ◽  
Sreekantha B. Jonnalagadda

RSC Advances ◽  
2019 ◽  
Vol 9 (53) ◽  
pp. 30768-30772 ◽  
Author(s):  
Mandlenkosi Robert Khumalo ◽  
Surya Narayana Maddila ◽  
Suresh Maddila ◽  
Sreekantha B. Jonnalagadda

A facile, swift and ecofriendly microwave-assisted multi-component/one-pot protocol is designed for the synthesis of novel pyrazolo-[3,4-b]-quinolines at ambient temperature in aqueous ethanol as a reaction medium.


ChemInform ◽  
2015 ◽  
Vol 46 (37) ◽  
pp. no-no
Author(s):  
Billel Belhani ◽  
Malika Berredjem ◽  
Marc Le Borgne ◽  
Zouhair Bouaziz ◽  
Jacques Lebreton ◽  
...  

2021 ◽  
Vol 08 ◽  
Author(s):  
Thais Cristina Mendonça Nogueiraa ◽  
Marcus Vinicius Nora de Souza

: Five- and six-membered N-heterocyclic compounds play an important role in medicinal chemistry and in the development of new drugs. In this manner, there is a constant demand for the development of novel biologically potent compounds and there is also an increasing pressure to develop alternative and more sustainable synthetic methodologies following the Green Chemistry principles. Thus, the present review aims to compile the latest progress in the use of ultrasound irradiation in water conditions to mediate the synthesis of five- and six-membered N-heterocyclic compounds in an environmentally benign manner.


RSC Advances ◽  
2015 ◽  
Vol 5 (34) ◽  
pp. 26625-26633 ◽  
Author(s):  
Mohsen Esmaeilpour ◽  
Jaber Javidi ◽  
Farzaneh Dehghani ◽  
Fatemeh Nowroozi Dodeji

Green synthesis of tetrahydrobenzo[b]pyran and dihydropyrano[3,2-c]chromene derivatives.


2010 ◽  
Vol 40 (24) ◽  
pp. 3609-3617 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Esmat Chehrehgosha Parashkuhi ◽  
Saeed Raoufmoghaddam ◽  
Mahdieh Sadeghpour

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