scholarly journals Changes in telomere length and telomerase activity in human bronchial epithelial cells induced by coal tar pitch extract

2015 ◽  
Vol 4 (6) ◽  
pp. 1535-1544 ◽  
Author(s):  
Feifei Feng ◽  
Yongli Yang ◽  
Zhitao Li ◽  
Jinyan Song ◽  
Hansong Zhu ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Telomere Length ◽  
Aromatic Hydrocarbons ◽  
Coal Tar ◽  
Telomerase Activity ◽  
Coal Tar Pitch ◽  
Human Bronchial Epithelial Cells ◽  
Bronchial Epithelial ◽  
Human Carcinogen ◽  
Polycyclic Aromatic

Coal tar pitch is a confirmed human carcinogen and is composed mainly of polycyclic aromatic hydrocarbons.

Modification of Coal Tar Pitch to Reduce the Carcinogenic Polycyclic Aromatic Hydrocarbons

2013 ◽  
Vol 295-298 ◽  
pp. 3098-3103 ◽  
Author(s):  
De Min He ◽  
Jun Guan ◽  
Di Wu ◽  
Shu Chang Zhao ◽  
Qiu Min Zhang
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Reaction Time ◽  
Epoxy Resin ◽  
Aromatic Hydrocarbons ◽  
Coal Tar ◽  
Coal Tar Pitch ◽  
Temperature Reaction ◽  
Polycyclic Aromatic ◽  
Soft Point

This research investigated on reducing carcinogenic polycyclic aromatic hydrocarbons(PAHs),especially benzo[a]pyrene (BaP) in coal tar pitch by modifying with the two selected modifiers: Paraformaldehyde and Epoxy Resin. The reaction emphasis on the change of temperature, reaction time and the quantity of the modifiers. The results indicated that Paraformaldehyde and Epoxy Resin could decrease the PAHs content greatly. The BaP decreasing rate reached 75.86% and 53.45% respectively. And the BaP equivalency content of the pitch decreased from 2.94% to 1.41% and 1.47% respectively. The properties of the modified coal tar pitch, including soft point (SP), toluene insolubles (TI), quinoline insolubles (QI) have changed a lot.

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