Targeted CT/MR dual mode imaging of human hepatocellular carcinoma using lactobionic acid-modified polyethyleneimine-entrapped gold nanoparticles

2017 ◽  
Vol 5 (13) ◽  
pp. 2395-2401 ◽  
Author(s):  
Du Li ◽  
Jia Yang ◽  
Shihui Wen ◽  
Mingwu Shen ◽  
Linfeng Zheng ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gold Nanoparticles ◽  
Mr Imaging ◽  
Human Hepatocellular Carcinoma ◽  
Dual Mode ◽  
Lactobionic Acid

Multifunctional PEI-entrapped gold nanoparticles modified with lactobionic acid enable efficient targeted dual mode CT/MR imaging of human hepatocellular carcinoma.

Targeted CT imaging of human hepatocellular carcinoma using low-generation dendrimer-entrapped gold nanoparticles modified with lactobionic acid

2015 ◽  
Vol 3 (2) ◽  
pp. 286-295 ◽  
Author(s):  
Yiyun Cao ◽  
Yao He ◽  
Hui Liu ◽  
Yu Luo ◽  
Mingwu Shen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gold Nanoparticles ◽  
Ct Imaging ◽  
Human Hepatocellular Carcinoma ◽  
Lactobionic Acid

Dendrimer-entrapped gold nanoparticles formed using low-generation dendrimers modified with PEGylated lactobionic acid as templates enable targeted CT imaging of human hepatocellular carcinoma.

scholarly journals Alginate/CaCO3 Hybrid Loaded with Sorafenib Tosylate and Gold Hexagons: A Model for Efficient Dual (Chemo-Radio) Treatment of HepG2 Cells

2021 ◽  
Author(s):  
Firas A. Sukkar ◽  
Medhat W. Shafaa ◽  
Mohamed S. El-Nagdy ◽  
Soheir S. Korraa ◽  
wael darwish
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Hepg2 Cells ◽  
Human Hepatocellular Carcinoma ◽  
The Novel ◽  
Chemotherapeutic Drug ◽  
Hydrophobic Drug ◽  
Γ Radiation ◽  
Different Doses

Abstract In this work, we investigated the combinatorial cytotoxic actions of the chemotherapeutic drug (sorafenib tosylate, ST) in synergism with γ-radiation on human hepatocellular carcinoma (HepG2) cells. The novel radiosensitizer, hexagonal gold nanoparticles, was prepared and utilized To enhance the radiobiological response of HepG2 cells. A well-designed nanoporous alginate/CaCO3 hybrid was prepared as a biocompatible/biodegradable nanocarrier for co-delivery of the hydrophobic drug and the hydrophilic radiosensitizer to the cancer cells. Incubation of HepG2 cells with the nanoprobes followed by different doses (0, 3 or 6 Gy) of γ-radiation resulted in significant reduction of the cells viability as a result of the synergistic (chemo-radiation) cytotoxic actions.

scholarly journals Targeted tumor dual mode CT/MR imaging using multifunctional polyethylenimine-entrapped gold nanoparticles loaded with gadolinium

Drug Delivery ◽  
2018 ◽  
Vol 25 (1) ◽  
pp. 178-186 ◽  
Author(s):  
Benqing Zhou ◽  
Zuogang Xiong ◽  
Peng Wang ◽  
Chen Peng ◽  
Mingwu Shen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Mr Imaging ◽  
Dual Mode

Multifunctional dendrimer-entrapped gold nanoparticles for dual mode CT/MR imaging applications

Biomaterials ◽  
2013 ◽  
Vol 34 (5) ◽  
pp. 1570-1580 ◽  
Author(s):  
Shihui Wen ◽  
Kangan Li ◽  
Hongdong Cai ◽  
Qian Chen ◽  
Mingwu Shen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Mr Imaging ◽  
Dual Mode
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