Chiral phosphoric acid catalyzed enantioselective N-alkylation of indoles with in situ generated cyclic N-acyl ketimines
A chiral SPINOL derived phosphoric acid-catalyzed asymmetric N-alkylation reaction of indoles with cyclic α-diaryl-substituted N-acyl imines, which are generated in situ from 3-aryl 3-hydroxyisoindo-linones, has been demonstrated.
2017 ◽
Vol 58
(2)
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pp. 145-151
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2016 ◽
Vol 14
(24)
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pp. 5751-5754
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2017 ◽
Vol 15
(35)
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pp. 7272-7276
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