Transition-metal-free α-arylation of nitroketones with diaryliodonium salts for the synthesis of tertiary α-aryl, α-nitro ketones

2019 ◽  
Vol 55 (1) ◽  
pp. 119-122 ◽  
Author(s):  
Yang An ◽  
Xiao-Ming Zhang ◽  
Ze-Yu Li ◽  
Wen-Hui Xiong ◽  
Run-Dong Yu ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
Diaryliodonium Salts ◽  
First Time

Transition-metal-free α-arylation of α-nitroketones with diaryliodonium salts has been developed for the first time and applied in the synthesis of tiletamine.

Transition Metal-Free O-Arylation of Quinoxalin-2-ones with Diaryliodonium Salts

Heterocycles ◽  
2021 ◽  
Vol 103 (1) ◽  
pp. 502
Author(s):  
Masami Kuriyama ◽  
Osamu Onomura ◽  
Yuki Mochizuki ◽  
Tsubasa Miyagi ◽  
Kosuke Yamamoto ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
Diaryliodonium Salts

Transition metal-free base-promoted arylation of sulfenate anions with diaryliodonium salts

2019 ◽  
Vol 6 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Lei Wang ◽  
Mingjie Chen ◽  
Junliang Zhang
Keyword(s):  
Transition Metal ◽  
Free Base ◽  
Metal Free ◽  
Diaryliodonium Salts

A base-promoted formal arylation of general sulfenate anions with diaryliodonium salts under transition-metal-free conditions has been described.

Transition-Metal-Free, Intermolecular Azidoheteroarylation of Alkenes: Efficient Access to β-Azidoalkylated Quinoxalinones and Preliminary Antifungal Evaluation Against Magnaporthe grisea

Synthesis ◽  
2020 ◽  
Vol 52 (16) ◽  
pp. 2395-2409
Author(s):  
Weiwei Qin ◽  
Zhaodong Li ◽  
Yiming Du ◽  
Yue Chen ◽  
Yun-Lin Liu
Keyword(s):  
Transition Metal ◽  
Magnaporthe Grisea ◽  
Single Step ◽  
Domino Reaction ◽  
Efficient Synthesis ◽  
Metal Free ◽  
Efficient Access ◽  
First Time ◽  
Antibacterial Evaluation ◽  
Addition Pathway

An efficient, PhI(OAc)2-mediated, radical azidoheteroarylation of alkenes under transition-metal-free conditions is reported by employing TMSN3 and quinoxalin-2(1H)-ones as coupling partners. This domino reaction allows an efficient synthesis of valuable orangoazides containing quinoxalin-2(1H)-one derivatives and could be extended to phosphinyl-alkylated quinoxalin-2(1H)-one in a single step in moderate to excellent yields under mild conditions, as demonstrated by the preliminary antibacterial evaluation against Magnaporthe grisea for the first time. Mechanistic studies revealed that this transformation undergoes a cascade addition pathway controlled by a polar radical.

Transition-Metal-Free N-Arylation of Carbazoles and C-Arylation of Tetrahydrocarbazoles by using Diaryliodonium Salts

2012 ◽  
Vol 1 (3) ◽  
pp. 218-221 ◽  
Author(s):  
Fenglou Guo ◽  
Limin Wang ◽  
Peiqi Wang ◽  
Jianjun Yu ◽  
Jianwei Han
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
Diaryliodonium Salts

The peroxodisulfate-assisted three-component benzylation of coumarins with styrenes and KSCN: A transition-metal-free approach for the synthesis of 3-(1-aryl-2-thiocyanatoethyl)-2H-chromen-2-one in ethyl lactate

2021 ◽  
Author(s):  
Palani Natarajan ◽  
Priya ◽  
Deachen Chuskit
Keyword(s):  
Transition Metal ◽  
Ethyl Lactate ◽  
Metal Free ◽  
Reaction Proceeds ◽  
First Time

The peroxodisulfate-assisted three-component benzylation of coumarins with styrenes and KSCN to 3-(1-aryl-2-thiocyanatoethyl)-2H-chromen-2-one is reported for the first time. This reaction proceeds via the consecutive addition of SCN radical to styrenes...

Application of primary halogenated hydrocarbons for the synthesis of 3-aryl and 3-alkyl indolizines

2017 ◽  
Vol 15 (23) ◽  
pp. 5016-5024 ◽  
Author(s):  
Yan Liu ◽  
Huayou Hu ◽  
Junyu Zhou ◽  
Wenhui Wang ◽  
Youliang He ◽  
...  
Keyword(s):  
Transition Metal ◽  
Halogenated Hydrocarbons ◽  
Tandem Reaction ◽  
Synthetic Route ◽  
Metal Free ◽  
First Time

A transition-metal-free synthetic route to 3-aryl and 3-alkyl indolizines from electron-deficient alkenes, pyridines and primary halogenated hydrocarbons is reported for the first time using a tandem reaction.

Metal-free enantioselective addition of nucleophilic silicon to aromatic aldehydes catalyzed by a [2.2]paracyclophane-based N-heterocyclic carbene catalyst

2017 ◽  
Vol 15 (15) ◽  
pp. 3202-3206 ◽  
Author(s):  
Ping An ◽  
Yuwen Huo ◽  
Zhen Chen ◽  
Chun Song ◽  
Yudao Ma
Keyword(s):  
Transition Metal ◽  
Aromatic Aldehydes ◽  
Metal Free ◽  
Enantioselective Addition ◽  
First Time

A transition metal-free enantioselective 1,2-silylation of aromatic aldehydes to yield chiral α-hydroxysilanes was developed for the first time.

Transition metal-free N-arylation of secondary amides through iodonium salts as aryne precursors

2016 ◽  
Vol 14 (43) ◽  
pp. 10185-10188 ◽  
Author(s):  
Ming Wang ◽  
Zhijian Huang
Keyword(s):  
Transition Metal ◽  
Iodonium Salts ◽  
Metal Free ◽  
Diaryliodonium Salts ◽  
Secondary Amides

A transition metal-free approach for N-arylation of secondary amides was developed via diaryliodonium salts as aryne precursors.

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