Iodine monobromide catalysed regioselective synthesis of 3-arylquinolines from α-aminoacetophenones and trans-β-nitrostyrenes

2019 ◽  
Vol 17 (2) ◽  
pp. 347-353 ◽  
Author(s):  
Radhakrishna Gattu ◽  
Santa Mondal ◽  
Saghir Ali ◽  
Abu T. Khan
Keyword(s):  
Efficient Method ◽  
Regioselective Synthesis ◽  
Iodine Monobromide

A simple and efficient method for regioselective synthesis of 3-arylquinolines is described from α-aminoacetophenones and trans-β-nitrostyrenes using 20 mol% iodine monobromide as a catalyst in acetonitrile solvent at 80 °C.

K2CO3 catalyzed regioselective synthesis of thieno[2,3-b]thiochromen-4-one oximes: access to the corresponding amine and nitroso derivatives

2017 ◽  
Vol 15 (26) ◽  
pp. 5625-5634 ◽  
Author(s):  
Karuna Mahato ◽  
Prasanta Ray Bagdi ◽  
Abu T. Khan
Keyword(s):  
Efficient Method ◽  
Cyclization Reaction ◽  
Regioselective Synthesis

An unprecedented and efficient method for the synthesis of useful thieno[2,3-b]thiochromen-4-one oximes is accomplished via a thio[3 + 2] cyclization reaction of 4-hydroxydithiocoumarins and trans-β-nitrostyrenes in the presence of 10 mol% K2CO3 in ethanol under reflux conditions.

Complementary and Regioselective Synthesis of Isomeric 3-[Isoxazol-3(or 5)-yl]indoles from β-Ethylthio-β-indolyl-α,β-unsaturated Ketones

Synthesis ◽  
2021 ◽  
Author(s):  
Haifeng Yu ◽  
Wenju Wang ◽  
Kehua Wang ◽  
Xue Zhang
Keyword(s):  
Efficient Method ◽  
Hydroxylamine Hydrochloride ◽  
Regioselective Synthesis ◽  
Unsaturated Ketones ◽  
Cyclocondensation Reaction

AbstractA simple and efficient method for the complementary and regioselective synthesis of isomeric 3-(isoxazol-5-yl)indoles and 3-(isoxazol-3-yl)indoles has been developed by the regioselective cyclocondensation reaction of β-ethylthio-β-indolyl-α,β-unsaturated ketones and hydroxylamine hydrochloride. It was found that the cyclocondensation reaction in the presence of excess NaOEt in refluxing EtOH gives 3-(isoxazol-5-yl)indoles in good yields, whereas using NaOAc in boiling AcOH gives 3-(isoxazol-3-yl)indoles in good yields.

Bifunctionalized Allenes, Part IX: An Efficient Method for Regioselective Synthesis of 4-Heteroatom-Functionalized Allenecarboxylates

2013 ◽  
Vol 24 (4) ◽  
pp. 322-331 ◽  
Author(s):  
Ivaylo K. Ivanov ◽  
Ivaylo D. Parushev ◽  
Valerij Ch. Christov
Keyword(s):  
Efficient Method ◽  
Regioselective Synthesis

Regioselective synthesis of 2,3′-biindoles mediated by an NBS-induced homo-coupling of indoles

2017 ◽  
Vol 15 (45) ◽  
pp. 9622-9629 ◽  
Author(s):  
Panpan Huang ◽  
Xiangjun Peng ◽  
Dan Hu ◽  
Huiwu Liao ◽  
Shaobin Tang ◽  
...  
Keyword(s):  
Efficient Method ◽  
Regioselective Synthesis ◽  
Carbazole Derivatives

An efficient method for the synthesis of 2,3′-biindole and [3,2-a]carbazole derivatives via an NBS-induced homo-coupling of indoles with high regioselectivity.

A base-promoted cascade reaction of α,β-unsaturated N-tosylhydrazones with o-hydroxybenzyl alcohols: highly regioselective synthesis of N-sec-alkylpyrazoles

2019 ◽  
Vol 17 (37) ◽  
pp. 8561-8570 ◽  
Author(s):  
Lian-Mei Chen ◽  
Juan Zhao ◽  
An-Jie Xia ◽  
Xiao-Qiang Guo ◽  
Ya Gan ◽  
...  
Keyword(s):  
Efficient Method ◽  
Cascade Reaction ◽  
Regioselective Synthesis

An efficient method for the synthesis of N-sec-alkylpyrazoles via a cascade reaction of α,β-unsaturated N-tosylhydrazones with ortho-hydroxybenzyl alcohols has been developed.

scholarly journals Bifunctionalized Allenes. Part XIII. A Convenient and Efficient Method for Regioselective Synthesis of Phosphorylated α-Hydroxyallenes with Protected and Unprotected Hydroxy Group

Molecules ◽  
2014 ◽  
Vol 19 (5) ◽  
pp. 6309-6329 ◽  
Author(s):  
Ismail Ismailov ◽  
Ivaylo Ivanov ◽  
Valerij Christov
Keyword(s):  
Hydroxy Group ◽  
Efficient Method ◽  
Regioselective Synthesis

scholarly journals Bifunctionalized Allenes. Part XXIII. An Efficient Method for Regioselective Synthesis of 5-Phosphorylated Allenecarboxylates

2020 ◽  
Vol 7 (3) ◽  
pp. 1-10
Author(s):  
Hasan H. Hasanov ◽  
Ivaylo K. Ivanov ◽  
Valerij Ch. Christov
Keyword(s):  
Efficient Method ◽  
Sigmatropic Rearrangement ◽  
Regioselective Synthesis

AbstractAn efficient method for regioselective synthesis of 5-(dimethoxyphosphoryl)-allenecarboxylates by an atom economical [2,3]-sigmatropic rearrangement of the mediated 3-(dimethoxyphosphanyloxy)-alk-4-ynoates is described. Alkyl 5-(dimethoxyphosphoryl)-alka-3,4-dienoates can be readily prepared via reaction of alkyl 3-hydroxy-alk-4-ynoates with dimethylchlorophosphite in the presence of a base. Alkyl 3-hydroxy-alk-4-ynoates were prepared by reaction of the metallated acetylenes with commercialy available alkyl 3-oxoalkanoates.

Tungstate-Catalyzed Decarboxylative Oxidation of N-Alkyl-.alpha.-amino Acids: An Efficient Method for Regioselective Synthesis of Nitrones

1994 ◽  
Vol 59 (21) ◽  
pp. 6170-6172 ◽  
Author(s):  
Shun-Ichi Murahashi ◽  
Yasushi Imada ◽  
Hiroaki Ohtake
Keyword(s):  
Amino Acids ◽  
Efficient Method ◽  
Regioselective Synthesis

One-pot three-component regioselective synthesis of C1-functionalised 3-arylbenzo[f]quinoline

RSC Advances ◽  
2016 ◽  
Vol 6 (14) ◽  
pp. 11675-11682 ◽  
Author(s):  
Radhakrishna Gattu ◽  
R. Sidick Basha ◽  
Prasanta Ray Bagdi ◽  
Abu T. Khan
Keyword(s):  
Aromatic Aldehyde ◽  
Efficient Method ◽  
Regioselective Synthesis ◽  
Camphorsulfonic Acid ◽  
One Pot

An efficient method for regioselective synthesis of C1-functionalised 3-arylbenzo[f]quinoline has been demonstrated using β-ketoester, 2-naphthylamine and aromatic aldehyde by employing camphorsulfonic acid as the catalyst in acetonitrile at 70 °C.

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