scholarly journals Highly diastereoselective synthesis of tricyclic fused-pyrans by sequential hydride shift mediated double C(sp3)–H bond functionalization

2018 ◽  
Vol 9 (37) ◽  
pp. 7327-7331 ◽  
Author(s):  
Keiji Mori ◽  
Nobuaki Umehara ◽  
Takahiko Akiyama
Keyword(s):  
Bronsted Acid ◽  
Brønsted Acid ◽  
Diastereoselective Synthesis ◽  
Bond Functionalization ◽  
Hydride Shift ◽  
Brönsted Acid ◽  
Acid Catalyzed

Highly diastereoselective synthesis of tricyclic fused-pyrans was achieved by Brønsted acid catalyzed double C(sp3)–H bond functionalization.

Synthesis of 3-Aryl-1-trifluoromethyltetrahydroisoquinolines by Brønsted Acid-Catalyzed C(sp3)H Bond Functionalization

2014 ◽  
Vol 357 (5) ◽  
pp. 901-906 ◽  
Author(s):  
Keiji Mori ◽  
Nobuaki Umehara ◽  
Takahiko Akiyama
Keyword(s):  
Bronsted Acid ◽  
Brønsted Acid ◽  
Bond Functionalization ◽  
Brönsted Acid ◽  
Acid Catalyzed

scholarly journals 3-Component synthesis of α-substituted sulfonamides via Brønsted acid-catalyzed C(sp3)–H bond functionalization of 2-alkylazaarenes

2016 ◽  
Vol 14 (24) ◽  
pp. 5525-5528 ◽  
Author(s):  
T. Beisel ◽  
J. Kirchner ◽  
T. Kaehler ◽  
J. Knauer ◽  
Y. Soltani ◽  
...  
Keyword(s):  
Bronsted Acid ◽  
Brønsted Acid ◽  
Bond Functionalization ◽  
Brönsted Acid ◽  
Acid Catalyzed

A Brønsted acid-catalyzed addition of 2-alkylazaarenes to in situ generated N-sulfonylimines through selective C(sp3)–H bond functionalization has been developed.

Brønsted Acid Catalyzed Domino 1,6-Addition/Intramolecular Cyclization­ Reactions: Diastereoselective Synthesis of Dihydro­coumarin Frameworks

Synthesis ◽  
2017 ◽  
Vol 50 (06) ◽  
pp. 1307-1314 ◽  
Author(s):  
Guang-Jian Mei ◽  
Zheng Cao ◽  
Gui-Xiang Zhou ◽  
Chun Ma ◽  
Kang Jiang
Keyword(s):  
Hydrogen Bonding ◽  
Crucial Role ◽  
Acid Catalysis ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Diastereoselective Synthesis ◽  
Quinone Methides ◽  
Hydrogen Bonding Interactions ◽  
Brönsted Acid ◽  
Acid Catalyzed

An efficient domino 1,6-addition/intramolecular cyclization reaction between para-quinone methides (p-QMs) and azlactones under Brønsted acid catalysis was established. A series of highly functionalized dihydrocoumarins were constructed in good to excellent yields (up to 96%) with excellent diastereoselectivities (all >20:1 d.r.). In this process, the Brønsted acid plays a crucial role not only in activating the two substrates, but also in controlling the diastereoselectivity of the reaction via hydrogen-bonding interactions. In addition, this protocol demonstrates the great practicability of utilizing p-QMs in domino reactions.

A Brønsted acid catalyzed tandem reaction for the diastereoselective synthesis of cyclobuta-fused tetrahydroquinoline carboxylic esters

2021 ◽  
Author(s):  
Valentina Marras ◽  
Pierluigi Caboni ◽  
Francesco Secci ◽  
Régis Guillot ◽  
David J. Aitken ◽  
...  
Keyword(s):  
Michael Addition ◽  
Tandem Reaction ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Diastereoselective Synthesis ◽  
Cyclization Process ◽  
Brönsted Acid ◽  
Acid Catalyzed ◽  
Carboxylic Esters

We have established a Brønsted acid catalyzed diastereoselective synthesis of diversely substituted cyclobuta-fused tetrahydroquinoline carboxylic esters through a new tandem aza-Michael addition-aza-Friedel–Crafts cyclization process.

Gold and Brønsted Acid Catalyzed Hydride Shift onto Allenes: Divergence in Product Selectivity

2011 ◽  
Vol 133 (20) ◽  
pp. 7696-7699 ◽  
Author(s):  
Benoit Bolte ◽  
Fabien Gagosz
Keyword(s):  
Bronsted Acid ◽  
Product Selectivity ◽  
Brønsted Acid ◽  
Hydride Shift ◽  
Brönsted Acid ◽  
Acid Catalyzed

Brønsted Acid Catalyzed Benzylic C–H Bond Functionalization of Azaarenes: Nucleophilic Addition to Nitroso Compounds

2014 ◽  
Vol 16 (14) ◽  
pp. 3664-3667 ◽  
Author(s):  
Xu Gao ◽  
Feng Zhang ◽  
Guojun Deng ◽  
Luo Yang
Keyword(s):  
Nucleophilic Addition ◽  
Nitroso Compounds ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Bond Functionalization ◽  
Brönsted Acid ◽  
Acid Catalyzed

Synthetic Scope of Brønsted Acid-Catalyzed Reactions of Carbonyl Compounds and Ethyl Diazoacetate

2021 ◽  
Author(s):  
Mizzanoor Rahaman ◽  
M. Shahnawaz Ali ◽  
Khorshada Jahan ◽  
Damon Hinz ◽  
Jawad Bin Belayet ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Ethyl Diazoacetate ◽  
Brönsted Acid ◽  
Acid Catalyzed ◽  
Catalyzed Reactions
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