scholarly journals Current status and future perspectives of gold nanoparticle vectors for siRNA delivery

2019 ◽  
Vol 7 (6) ◽  
pp. 876-896 ◽  
Author(s):  
Álvaro Artiga ◽  
Inés Serrano-Sevilla ◽  
Laura De Matteis ◽  
Scott G. Mitchell ◽  
Jesús M. de la Fuente

Discovering the vast therapeutic potential of siRNA opened up new clinical research areas focussing on a number of diseases and applications; however significant problems with siRNA stability and delivery have hindered its clinical applicability.

Author(s):  
Mukesh Yadav ◽  
Nirmala Sehrawat ◽  
Sunil Kumar ◽  
Anil Kumar Sharma ◽  
Nipunjot Kaur ◽  
...  

2017 ◽  
Vol 118 (7) ◽  
pp. 1634-1638 ◽  
Author(s):  
Mina Hosseini ◽  
Seyed Mahdi Hassanian ◽  
Elham Mohammadzadeh ◽  
Soodabeh ShahidSales ◽  
Mina Maftouh ◽  
...  

Author(s):  
Apoorva Singh ◽  
Sanjukta Dasgupta ◽  
Anindita Bhattacharya ◽  
Gayatri Mukherjee ◽  
Koel Chaudhury

2018 ◽  
Vol 23 (37) ◽  
pp. 5760-5765 ◽  
Author(s):  
Antonio Gambardella ◽  
Angelo Labate ◽  
Laura Mumoli ◽  
Iscia Lopes-Cendes ◽  
Fernando Cendes

2020 ◽  
Vol 23 (8) ◽  
pp. 687-698 ◽  
Author(s):  
Houda N. Washah ◽  
Elliasu Y. Salifu ◽  
Opeyemi Soremekun ◽  
Ahmed A. Elrashedy ◽  
Geraldene Munsamy ◽  
...  

For the past few decades, the mechanisms of immune responses to cancer have been exploited extensively and significant attention has been given into utilizing the therapeutic potential of the immune system. Cancer immunotherapy has been established as a promising innovative treatment for many forms of cancer. Immunotherapy has gained its prominence through various strategies, including cancer vaccines, monoclonal antibodies (mAbs), adoptive T cell cancer therapy, and immune checkpoint therapy. However, the full potential of cancer immunotherapy is yet to be attained. Recent studies have identified the use of bioinformatics tools as a viable option to help transform the treatment paradigm of several tumors by providing a therapeutically efficient method of cataloging, predicting and selecting immunotherapeutic targets, which are known bottlenecks in the application of immunotherapy. Herein, we gave an insightful overview of the types of immunotherapy techniques used currently, their mechanisms of action, and discussed some bioinformatics tools and databases applied in the immunotherapy of cancer. This review also provides some future perspectives in the use of bioinformatics tools for immunotherapy.


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