scholarly journals Therapeutic Potential of Citrus Flavonoid Naringin in Management of Osteoporosis: Current Status and Future Perspectives

2022 ◽  
pp. 527-532
Author(s):  
Mukesh Yadav ◽  
Nirmala Sehrawat ◽  
Sunil Kumar ◽  
Anil Kumar Sharma ◽  
Nipunjot Kaur ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Current Status ◽  
Future Perspectives

scholarly journals Current status and future perspectives of gold nanoparticle vectors for siRNA delivery

2019 ◽  
Vol 7 (6) ◽  
pp. 876-896 ◽  
Author(s):  
Álvaro Artiga ◽  
Inés Serrano-Sevilla ◽  
Laura De Matteis ◽  
Scott G. Mitchell ◽  
Jesús M. de la Fuente
Keyword(s):  
Clinical Research ◽  
Gold Nanoparticle ◽  
Therapeutic Potential ◽  
Sirna Delivery ◽  
Current Status ◽  
Future Perspectives ◽  
Research Areas ◽  
Clinical Applicability

Discovering the vast therapeutic potential of siRNA opened up new clinical research areas focussing on a number of diseases and applications; however significant problems with siRNA stability and delivery have hindered its clinical applicability.

Therapeutic Potential of Curcumin in Treatment of Pancreatic Cancer: Current Status and Future Perspectives

2017 ◽  
Vol 118 (7) ◽  
pp. 1634-1638 ◽  
Author(s):  
Mina Hosseini ◽  
Seyed Mahdi Hassanian ◽  
Elham Mohammadzadeh ◽  
Soodabeh ShahidSales ◽  
Mina Maftouh ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Potential ◽  
Current Status ◽  
Future Perspectives

Therapeutic potential of curcumin in endometrial disorders: current status and future perspectives

2021 ◽  
Author(s):  
Apoorva Singh ◽  
Sanjukta Dasgupta ◽  
Anindita Bhattacharya ◽  
Gayatri Mukherjee ◽  
Koel Chaudhury
Keyword(s):  
Therapeutic Potential ◽  
Current Status ◽  
Future Perspectives

Role of Pharmacogenomics in Antiepileptic Drug Therapy: Current Status and Future Perspectives

2018 ◽  
Vol 23 (37) ◽  
pp. 5760-5765 ◽  
Author(s):  
Antonio Gambardella ◽  
Angelo Labate ◽  
Laura Mumoli ◽  
Iscia Lopes-Cendes ◽  
Fernando Cendes
Keyword(s):  
Drug Therapy ◽  
Antiepileptic Drug ◽  
Current Status ◽  
Future Perspectives ◽  
Antiepileptic Drug Therapy

Integrating Bioinformatics Strategies in Cancer Immunotherapy: Current and Future Perspectives

2020 ◽  
Vol 23 (8) ◽  
pp. 687-698 ◽  
Author(s):  
Houda N. Washah ◽  
Elliasu Y. Salifu ◽  
Opeyemi Soremekun ◽  
Ahmed A. Elrashedy ◽  
Geraldene Munsamy ◽  
...  
Keyword(s):  
Cancer Immunotherapy ◽  
Therapeutic Potential ◽  
Cell Cancer ◽  
Full Potential ◽  
Future Perspectives ◽  
The Past ◽  
Bioinformatics Tools ◽  
Treatment Paradigm ◽  
Immunotherapy Of Cancer ◽  
Significant Attention

For the past few decades, the mechanisms of immune responses to cancer have been exploited extensively and significant attention has been given into utilizing the therapeutic potential of the immune system. Cancer immunotherapy has been established as a promising innovative treatment for many forms of cancer. Immunotherapy has gained its prominence through various strategies, including cancer vaccines, monoclonal antibodies (mAbs), adoptive T cell cancer therapy, and immune checkpoint therapy. However, the full potential of cancer immunotherapy is yet to be attained. Recent studies have identified the use of bioinformatics tools as a viable option to help transform the treatment paradigm of several tumors by providing a therapeutically efficient method of cataloging, predicting and selecting immunotherapeutic targets, which are known bottlenecks in the application of immunotherapy. Herein, we gave an insightful overview of the types of immunotherapy techniques used currently, their mechanisms of action, and discussed some bioinformatics tools and databases applied in the immunotherapy of cancer. This review also provides some future perspectives in the use of bioinformatics tools for immunotherapy.

Stem Cell Transplantation: A Promising Therapy for Spinal Cord Injury

2020 ◽  
Vol 15 (4) ◽  
pp. 321-331 ◽  
Author(s):  
Zhe Gong ◽  
Kaishun Xia ◽  
Ankai Xu ◽  
Chao Yu ◽  
Chenggui Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Therapeutic Potential ◽  
Embryonic Stem ◽  
Current Status ◽  
Cord Injury

Spinal Cord Injury (SCI) causes irreversible functional loss of the affected population. The incidence of SCI keeps increasing, resulting in huge burden on the society. The pathogenesis of SCI involves neuron death and exotic reaction, which could impede neuron regeneration. In clinic, the limited regenerative capacity of endogenous cells after SCI is a major problem. Recent studies have demonstrated that a variety of stem cells such as induced Pluripotent Stem Cells (iPSCs), Embryonic Stem Cells (ESCs), Mesenchymal Stem Cells (MSCs) and Neural Progenitor Cells (NPCs) /Neural Stem Cells (NSCs) have therapeutic potential for SCI. However, the efficacy and safety of these stem cellbased therapy for SCI remain controversial. In this review, we introduce the pathogenesis of SCI, summarize the current status of the application of these stem cells in SCI repair, and discuss possible mechanisms responsible for functional recovery of SCI after stem cell transplantation. Finally, we highlight several areas for further exploitation of stem cells as a promising regenerative therapy of SCI.

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