Effect of crystal growth kinetics on the formation of liquid inclusions in tetramethylpyrazine crystals

CrystEngComm ◽  
2020 ◽  
Vol 22 (11) ◽  
pp. 1991-2001 ◽  
Author(s):  
Yaoguo Wang ◽  
Nuoyang Zhang ◽  
Baohong Hou ◽  
Qiuxiang Yin ◽  
Junbo Gong ◽  
...  

Inclusion of mother liquids inside the pharmaceutical crystals poses a great challenge and threat to the product quality and purification efficiency. Herein we demonstrate how growth kinetics tune the formation of liquid inclusion and its occluded mechanism.

2013 ◽  
Vol 215-216 ◽  
pp. 903-912 ◽  
Author(s):  
Mary Hanhoun ◽  
Ludovic Montastruc ◽  
Catherine Azzaro-Pantel ◽  
Béatrice Biscans ◽  
Michèle Frèche ◽  
...  

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