Direct catalytic asymmetric synthesis of α-chiral primary amines

2020 ◽  
Vol 49 (17) ◽  
pp. 6141-6153
Author(s):  
Qin Yin ◽  
Yongjie Shi ◽  
Jingxin Wang ◽  
Xumu Zhang

This review highlights the state-of-the-art catalytic methods for the direct asymmetric synthesis of α-chiral primary amines and demonstrates their utility in the construction of molecular complexities.

2021 ◽  
Author(s):  
Guang-Jian Mei ◽  
Wai Lean Koay ◽  
Chuan Xiang Alvin Tan ◽  
Yixin Lu

Pyrroloindolines are widely present in natural products. In this review, we summarize state-of-the-art of catalytic asymmetric synthesis of pyrroloindolines, as well as related applications to natural products total synthesis.


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