An efficient synthesis of oxazolines via a cascade reaction between azaoxyallyl cations and 1,2-benzisoxazoles

2019 ◽  
Vol 17 (32) ◽  
pp. 7526-7530 ◽  
Author(s):  
Li Sun ◽  
Yi Liu ◽  
Yankai Wang ◽  
Yuanyuan Li ◽  
Zhiwen Liu ◽  
...  
Keyword(s):  
Cycloaddition Reaction ◽  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Mild Conditions ◽  
Highly Efficient

A highly efficient 3 + 2 cycloaddition reaction with azaoxyallyl cation C–O terminals under mild conditions has been developed.

New efficient synthesis of benzofuro[2,3-b]pyrroles utilizing a reactive nitrilium trapping approach by an acid-promoted cascade addition/cyclization sequence

2020 ◽  
Vol 44 (9) ◽  
pp. 3632-3636
Author(s):  
Sandip Gangadhar Balwe ◽  
Yeon Tae Jeong
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
One Pot ◽  
Highly Efficient

The first p-TSA·H2O-catalyzed highly efficient one-pot cascade reaction for the synthesis of novel fused tricyclic benzofuro[2,3-b]pyrroles has been discovered.

Introduction of N,N'-disulfonylhydrazines as new sulfonylating reagents for highly efficient synthesis of (E)-β-iodovinyl arenesulfones under mild conditions

2020 ◽  
Vol 31 (7) ◽  
pp. 1877-1880
Author(s):  
Dongping Luo ◽  
Lin Min ◽  
Weiping Zheng ◽  
Lidong Shan ◽  
Xinyan Wang ◽  
...  
Keyword(s):  
Efficient Synthesis ◽  
Mild Conditions ◽  
Highly Efficient

Copper(II)-Promoted Oxidation/[3+2]Cycloaddition/Aromatization Cascade: Efficient Synthesis of Tetrasubstituted NH-Pyrrole from Chalcones and Iminodiacetates

Synlett ◽  
2019 ◽  
Vol 30 (12) ◽  
pp. 1442-1446 ◽  
Author(s):  
Zhang-qi Lin ◽  
Chao-dong Li ◽  
Zi-chun Zhou ◽  
Shuai Xue ◽  
Jian-rong Gao ◽  
...  
Keyword(s):  
Efficient Method ◽  
Cascade Reaction ◽  
Oxidative Cyclization ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
Highly Efficient ◽  
Wide Range ◽  
Reaction Proceeds

A simple and highly efficient method for the preparation of tetrasubstituted NH-pyrrole from a wide range of chalcones and diethyl iminodiacetates via a Cu(OAc)2-promoted oxidation/[3+2]cycloaddition/aromatization cascade reaction has been developed. This reaction proceeds through dehydrogenations, deamination, and oxidative cyclization, affording the corresponding products in good to excellent yields. This convenient methodology for constructing tetrasubstituted NH-pyrroles has several advantages over existing methods, such as the use of easily accessible chalcones and readily available diethyl iminodiacetates, and mild reaction conditions. A wide range of substrates are tolerated.

ChemInform Abstract: Efficient Synthesis of Phenanthridines Using Hendrickson Reagent Initiated Cascade Reaction under Mild Conditions.

ChemInform ◽  
2010 ◽  
Vol 41 (44) ◽  
pp. no-no
Author(s):  
Jie Xi ◽  
Qing-Li Dong ◽  
Guan-Sai Liu ◽  
Shaozhong Wang ◽  
Lin Chen ◽  
...  
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Mild Conditions

Highly efficient synthesis of cyclic carbonates from carbon dioxide and epoxides catalyzed by ionic liquid [Heemim][ZrCl5]

RSC Advances ◽  
2015 ◽  
Vol 5 (83) ◽  
pp. 67886-67891 ◽  
Author(s):  
Yu-Lin Hu ◽  
Ming Lu ◽  
Xue-Lin Yang
Keyword(s):  
Carbon Dioxide ◽  
Ionic Liquid ◽  
Cycloaddition Reaction ◽  
Cyclic Carbonates ◽  
Efficient Synthesis ◽  
Highly Efficient

A facile and efficient synthesis of cyclic carbonates by cycloaddition reaction is described.

ChemInform Abstract: Highly Efficient Synthesis of Aldenamines from Carboxamides by Iridium-Catalyzed Silane-Reduction/Dehydration under Mild Conditions.

ChemInform ◽  
2009 ◽  
Vol 40 (30) ◽  
Author(s):  
Yukihiro Motoyama ◽  
Masaharu Aoki ◽  
Naoki Takaoka ◽  
Ryuta Aoto ◽  
Hideo Nagashima
Keyword(s):  
Efficient Synthesis ◽  
Mild Conditions ◽  
Highly Efficient

Synthesis of Bisflavanol-Type Natural Products and Their Analogues­ via Self-Coupling of C8-Methylol Catechin Derivatives

Synthesis ◽  
2019 ◽  
Vol 51 (16) ◽  
pp. 3127-3141
Author(s):  
Deng-Ming Huang ◽  
Hui-Jing Li ◽  
Yan Zhao ◽  
Yan-Chao Wu
Keyword(s):  
Natural Products ◽  
Coupling Mechanism ◽  
The Novel ◽  
Efficient Synthesis ◽  
Metal Free ◽  
Mild Conditions ◽  
Highly Efficient ◽  
Acid Catalyzed

A highly efficient and regioselective self-coupling of C8-methylol catechin derivatives is developed for the synthesis of dimeric flavanol analogues under metal-free and mild conditions. Its applicability is showcased by the efficient synthesis of bisflavanol-type natural products bis-8,8′-catechinylmethane, bis-8,8′-epicatechinylmethane, talienbisflavan A, and oolonghomobisflavan A. The novel self-coupling mechanism sheds new light on the classical Friedel–Crafts alkylation mechanism in acid-catalyzed catechin–formaldehyde condensation.

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