A sensitive cyclic signal amplification fluorescence strategy for determination of methyltransferase activity based on graphene oxide and RNase H

2019 ◽  
Vol 7 (29) ◽  
pp. 4520-4527 ◽  
Author(s):  
Han Zhao ◽  
Changbei Ma ◽  
Ying Yan ◽  
Mingjian Chen

A sensitive fluorometric method for DNA methyltransferase activity detection based on graphene oxide and RNase H-assisted signal amplification.

The Analyst ◽  
2015 ◽  
Vol 140 (12) ◽  
pp. 4076-4082 ◽  
Author(s):  
Yefei Ma ◽  
Lini Chen ◽  
Liangliang Zhang ◽  
Suqi Liao ◽  
Jingjin Zhao

A sensitive fluorescence detection method for DNA methyltransferase is developed based on graphene oxide and T7 exonuclease-assisted signal amplification.


2019 ◽  
Vol 7 (43) ◽  
pp. 6789-6795 ◽  
Author(s):  
Huaijia Xue ◽  
Kaiyang Chen ◽  
Qing Zhou ◽  
Deng Pan ◽  
Yuanjian Zhang ◽  
...  

An Sb2Se3/graphene oxide composite was applied as both the photoelectrochemical probe and substrate for biomolecule conjugation for the construction of a “signal-off” sandwich-type biosensor for DNA methyltransferase activity detection.


2015 ◽  
Vol 51 (73) ◽  
pp. 13968-13971 ◽  
Author(s):  
Yan Zhang ◽  
Wen-jing Xu ◽  
Ya-ping Zeng ◽  
Chun-yang Zhang

We develop transcription-mediated duplex-specific nuclease-assisted cyclic signal amplification for sensitive detection of DNA methyltransferase activity.


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