One-pot synthesis of trypsin-based magnetic metal–organic frameworks for highly efficient proteolysis

2020 ◽  
Vol 8 (21) ◽  
pp. 4642-4647
Author(s):  
Chao Zhong ◽  
Zhixian Lei ◽  
Huan Huang ◽  
Mingyue Zhang ◽  
Zongwei Cai ◽  
...  

A facile approach was developed for one-pot synthesis of trypsin-based magnetic ZIF-8, which could be applied as an immobilized enzyme microreactor for rapid digestion of proteins.

2017 ◽  
Vol 490 ◽  
pp. 685-694 ◽  
Author(s):  
Muhammad Rizwan Azhar ◽  
Hussein Rasool Abid ◽  
Hongqi Sun ◽  
Vijay Periasamy ◽  
Moses O. Tadé ◽  
...  

CrystEngComm ◽  
2018 ◽  
Vol 20 (8) ◽  
pp. 1087-1093 ◽  
Author(s):  
Xuechuan Gao ◽  
Yuewu Wang ◽  
Guanfeng Ji ◽  
Ruixue Cui ◽  
Zhiliang Liu

A one-pot process has been developed for the synthesis of hierarchical-pore metal–organic frameworks, aimed at loading large and small drug molecules simultaneously.


2019 ◽  
Author(s):  
Monika Nehra ◽  
Deepak Kedia ◽  
Neeraj Dilbaghi ◽  
Ashraf Aly Hassan ◽  
Sandeep Kumar

RSC Advances ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 1995-2003 ◽  
Author(s):  
Hoda Mollabagher ◽  
Salman Taheri ◽  
Mohammad majid Mojtahedi ◽  
SeyedAmirhossein Seyedmousavi

The present work describes the catalytic activity of Cu-MOF for the one-pot synthesis of tacrine derivatives via a four-component reaction of 2-hydroxynaphthalene-1,4-dione, aldehydes, malononitrile and cycloketones in the presence of AlCl3.


2019 ◽  
Vol 55 (51) ◽  
pp. 7319-7322 ◽  
Author(s):  
Benjamin Slater ◽  
So-On Wong ◽  
Andrew Duckworth ◽  
Andrew J. P. White ◽  
Matthew R. Hill ◽  
...  

A visual representation of waste PLA being upcycled to a lactate containing MOF, ZnBLD–dPLA.


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