Recognition triggered assembly of split aptamers to initiate a hybridization chain reaction for wash-free and amplified detection of exosomes

2020 ◽  
Vol 56 (63) ◽  
pp. 9024-9027 ◽  
Author(s):  
Juan Chen ◽  
Jinlu Tang ◽  
Hong-Min Meng ◽  
Zhuo Liu ◽  
Lin Wang ◽  
...  
Keyword(s):  
Hybridization Chain Reaction ◽  
Chain Reaction

A novel split aptamer-based system was developed for the amplified detection of exosomes in situ assisted by a target-induced HCR.

A new method for the in situ assay of α-glucosidase activity and inhibitor screening through an enzyme substrate-mediated DNA hybridization chain reaction

2019 ◽  
Vol 43 (24) ◽  
pp. 9458-9465
Author(s):  
Xiquan Yue ◽  
Lihong Su ◽  
Xu Chen ◽  
Junfeng Liu ◽  
Longpo Zheng ◽  
...  
Keyword(s):  
Small Molecule ◽  
Dna Hybridization ◽  
New Method ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Inhibitor Screening ◽  
Glucosidase Activity ◽  
Enzyme Substrate ◽  
In Situ Assay

The strategy is based on small molecule-mediated hybridization chain reaction.

Nanogold-based bio-bar codes for label-free immunosensing of proteins coupling with an in situ DNA-based hybridization chain reaction

2012 ◽  
Vol 48 (100) ◽  
pp. 12207 ◽  
Author(s):  
Jun Zhou ◽  
Mingdi Xu ◽  
Dianping Tang ◽  
Zhuangqiang Gao ◽  
Juan Tang ◽  
...  
Keyword(s):  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Bar Codes

I-Motif-Based in Situ Bipedal Hybridization Chain Reaction for Specific Activatable Imaging and Enhanced Delivery of Antisense Oligonucleotides

2019 ◽  
Vol 91 (19) ◽  
pp. 12538-12545 ◽  
Author(s):  
Wenjie Ma ◽  
Biao Chen ◽  
Shanzi Zou ◽  
Ruichen Jia ◽  
Hong Cheng ◽  
...  
Keyword(s):  
Antisense Oligonucleotides ◽  
Hybridization Chain Reaction ◽  
Chain Reaction

scholarly journals Combined microRNA and mRNA detection in mammalian retinas by in situ hybridization chain reaction

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Pei Zhuang ◽  
Huanqing Zhang ◽  
Ryan M. Welchko ◽  
Robert C. Thompson ◽  
Shunbin Xu ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Mrna Detection

Facilitating In Situ Tumor Imaging with a Tetrahedral DNA Framework‐Enhanced Hybridization Chain Reaction Probe

2022 ◽  
pp. 2109728
Author(s):  
Bowen Zhang ◽  
Taoran Tian ◽  
Dexuan Xiao ◽  
Shaojingya Gao ◽  
Xiaoxiao Cai ◽  
...  
Keyword(s):  
Tumor Imaging ◽  
Hybridization Chain Reaction ◽  
Chain Reaction

Hybridization Chain Reaction (HCR) In Situ Protocol v1

protocols.io ◽  
2021 ◽  
Author(s):  
Heather S ◽  
Gabby Jerz ◽  
Sophia not provided ◽  
Jenny not provided ◽  
Aaron Pomerantz ◽  
...  
Keyword(s):  
Hybridization Chain Reaction ◽  
Chain Reaction
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