Rhamnetin decelerates the elimination and enhances the antitumor effect of the molecular-targeting agent sorafenib in hepatocellular carcinoma cells via the miR-148a/PXR axis

2021 ◽  
Author(s):  
Boan Li ◽  
Fan Feng ◽  
Hui Jia ◽  
Qiyu Jiang ◽  
Shuang Cao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Resistance ◽  
Antitumor Effect ◽  
Pregnane X Receptor ◽  
Carcinoma Cells ◽  
Molecular Targeting ◽  
Hepatocellular Carcinoma Cells ◽  
Molecular Targeting Agent

The pregnane X receptor (PXR) mediates the resistance of sorafenib in hepatocellular carcinoma (HCC) by promoting the clearance or elimination of sorafenib via the drug resistance-related downstream genes of the PXR. Rhamnetin drepresses the activation of PXR via miR-148a.

scholarly journals Triclosan treatment decreased the antitumor effect of sorafenib on hepatocellular carcinoma cells

2018 ◽  
Vol Volume 11 ◽  
pp. 2945-2954 ◽  
Author(s):  
Man Wu ◽  
Guanren Zhao ◽  
Xiaomei Zhuang ◽  
Tianhong Zhang ◽  
Ce Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Antitumor Effect ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

scholarly journals Chelidonine enhances the antitumor effect of lenvatinib on hepatocellular carcinoma cells

2019 ◽  
Vol Volume 12 ◽  
pp. 6685-6697 ◽  
Author(s):  
Fang-jie Hou ◽  
Li-xiao Guo ◽  
Kai-yan Zheng ◽  
Jun-na Song ◽  
Qian Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Antitumor Effect ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

scholarly journals Caffeine Increases the Antitumor Effect of Cisplatin in Human Hepatocellular Carcinoma Cells

2012 ◽  
Vol 35 (3) ◽  
pp. 400-407 ◽  
Author(s):  
Yohei Kawano ◽  
Masashi Nagata ◽  
Takafumi Kohno ◽  
Akihiro Ichimiya ◽  
Tomomi Iwakiri ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Antitumor Effect ◽  
Carcinoma Cells ◽  
Human Hepatocellular Carcinoma ◽  
Hepatocellular Carcinoma Cells ◽  
Human Hepatocellular Carcinoma Cells

Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MDR1 ribozymes

Hepatology ◽  
2002 ◽  
Vol 36 (4) ◽  
pp. 874-884 ◽  
Author(s):  
Matthes Huesker ◽  
Yvonne Folmer ◽  
Michaela Schneider ◽  
Christine Fulda ◽  
Hubert E. Blum ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Resistance ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Adenoviral Delivery

scholarly journals Effects of Mitochondrial Translocation of Telomerase on Drug Resistance in Hepatocellular Carcinoma Cells

2015 ◽  
Vol 6 (2) ◽  
pp. 151-159 ◽  
Author(s):  
Jing Yan ◽  
Yuan Zhou ◽  
DaiXing Chen ◽  
LiLi Li ◽  
Xin Yang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Resistance ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Mitochondrial Translocation
Sign in / Sign up

Export Citation Format

Share Document