Ammonium hydroxide as the ultimate amino source for the synthesis of N-unprotected 3-tetrasubstituted aminooxindoles via catalyst-free direct amination

2020 ◽  
Vol 22 (6) ◽  
pp. 1837-1841
Author(s):  
Jing Yue ◽  
Xi-Tao Ma ◽  
Xiong-Li Liu ◽  
Jun-Xin Wang ◽  
Xiong-Wei Liu ◽  
...  

The direct use of ammonium hydroxide in amination for the synthesis of primary amines is considered to be one of the major challenges in synthetic organic chemistry.

2020 ◽  
Vol 24 (18) ◽  
pp. 2181-2191
Author(s):  
Li Wang ◽  
Ziyi Li ◽  
Jiang Liu ◽  
Jianlin Han ◽  
Hiroki Moriwaki ◽  
...  

The development of an efficient and mild synthetic methodology for the construction of bioactive fluorine-containing molecules represents one of the hot research topics in general synthetic organic chemistry. In this review, some recent progresses achieved in the development of detrifluoroacetylatively generated mono-fluorinated enolates via CC bond cleavage and their asymmetric nucleophilic reactions for assembly of chiral quaternary C-F center containing compounds.


1973 ◽  
Vol 50 (9) ◽  
pp. 645
Author(s):  
H. A. Clark ◽  
J. C. Marshall ◽  
T. L. Isenhour

Author(s):  
Thaipparambil Aneeja ◽  
Mohan Neetha ◽  
C. M. A. Afsina ◽  
Gopinathan Anilkumar

Manganese-catalyzed C–H activation has become an emerging area in organic chemistry. These efficient and eco-friendly manganese catalysed reactions provides new opportunities in the field of synthetic organic chemistry.


2021 ◽  
Vol 50 (13) ◽  
pp. 4445-4469
Author(s):  
Jimmy Nelson Appaturi ◽  
Rajni Ratti ◽  
Bao Lee Phoon ◽  
Samaila Muazu Batagarawa ◽  
Israf Ud Din ◽  
...  

One of the most crucial attributes of synthetic organic chemistry is to design organic reactions under the facets of green chemistry for the sustainable production of chemicals.


ChemInform ◽  
2006 ◽  
Vol 37 (42) ◽  
Author(s):  
Kiichiro Totani ◽  
Shinya Hagihara ◽  
Yukishige Ito

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