Recent Developments in the Asymmetric Detrifluoroacetylative Reactions of in situ Generated Mono-Fluorinated Enolates

2020 ◽  
Vol 24 (18) ◽  
pp. 2181-2191
Author(s):  
Li Wang ◽  
Ziyi Li ◽  
Jiang Liu ◽  
Jianlin Han ◽  
Hiroki Moriwaki ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Bond Cleavage ◽  
Synthetic Methodology ◽  
Research Topics ◽  
Synthetic Organic Chemistry ◽  
Nucleophilic Reactions ◽  
F Center ◽  
Recent Developments

The development of an efficient and mild synthetic methodology for the construction of bioactive fluorine-containing molecules represents one of the hot research topics in general synthetic organic chemistry. In this review, some recent progresses achieved in the development of detrifluoroacetylatively generated mono-fluorinated enolates via CC bond cleavage and their asymmetric nucleophilic reactions for assembly of chiral quaternary C-F center containing compounds.

Functionalised Polymers: Recent Developments and New Applications in Synthetic Organic Chemistry

Synthesis ◽  
1997 ◽  
Vol 1997 (11) ◽  
pp. 1217-1239 ◽  
Author(s):  
Stephen J. Shuttleworth ◽  
Allin ◽  
Pradeep K. Sharma
Keyword(s):  
Organic Chemistry ◽  
Synthetic Organic Chemistry ◽  
Recent Developments ◽  
New Applications

Recent Developments in the Use of Supercritical CO2 in Synthetic Organic Chemistry

ChemInform ◽  
2003 ◽  
Vol 34 (50) ◽  
Author(s):  
Franck Furno ◽  
Peter Licence ◽  
Steven M. Howdle ◽  
Martyn Poliakoff
Keyword(s):  
Organic Chemistry ◽  
Supercritical Co2 ◽  
Synthetic Organic Chemistry ◽  
Recent Developments

scholarly journals Endo-Selective Construction of Spiro-[butyrolactone-pyrrolidine] via Ag(I)/CAAA-Amidphos-Catalyzed 1,3-Dipolar Cycloaddition between Azomethine Ylides and α-Methylene-γ-Butyrolactone

Catalysts ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 28 ◽  
Author(s):  
Qinglin Hou ◽  
Yaoyao You ◽  
Xinluo Song ◽  
Yingxia Wang ◽  
Ke Chen ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Catalytic System ◽  
Azomethine Ylides ◽  
Dipolar Cycloaddition ◽  
Effective Strategy ◽  
Optimal Conditions ◽  
One Pot ◽  
Synthetic Organic Chemistry ◽  
Quaternary Stereocenter

Construction of spirocyclic pyrrolidines bearing a spiro quaternary stereocenter is an enormous challenge in synthetic organic chemistry. In this report, we introduce a Ag(I)/CAAA-amidphos-catalyzed enantioselective 1,3-dipolar cycloaddition between azomethine ylides and α-methylene-γ-butyrolactone as an effective strategy for the construction of excellent endo-selective spiro-[butyrolactone-pyrrolidine] derivatives. Meanwhile, the catalytic system was also successfully applied in the three-component one-pot reaction of azomethine ylides formed in situ under the action of N,N′-diisopropylcarbodiimide serving as a dehydrator. Under the optimal conditions, endo-pyrrolidine derivatives bearing a spiro quaternary stereocenter were obtained with high to excellent yields (up to 95% yield) and enantioselectivities (up to 93% ee).

Construction of Carbon-Carbon and Carbon-Heteroatom Bonds: Enabled by Visible Light

2020 ◽  
Vol 24 (1) ◽  
pp. 44-73 ◽  
Author(s):  
Animesh Mondal ◽  
Chhanda Mukhopadhyay
Keyword(s):  
Organic Chemistry ◽  
Visible Light ◽  
Small Molecules ◽  
Environmentally Benign ◽  
Present Review ◽  
Synthetic Methodology ◽  
Environment Friendly ◽  
Synthetic Organic Chemistry ◽  
The Past ◽  
Green Strategy

The present review provides an overview of visible light-mediated environment- friendly approaches over the past decade for the formation of carbon-carbon and carbon-heteroatom framework. This area has recently emerged as a versatile, environmentally benign and green platform for the development of a highly sustainable synthetic methodology. According to the recent advancements, visible light has come to the forefront in synthetic organic chemistry as a powerful green strategy for the activation of small molecules.

Recent developments in the synthesis of five- and six-membered N-heterocycles from dicarbonyl compounds

2021 ◽  
Vol 25 ◽  
Author(s):  
Navjeet Kaur ◽  
Pranshu Bhardwaj ◽  
Mansi Gupta
Keyword(s):  
Organic Chemistry ◽  
Transition Metals ◽  
Heterocyclic Compounds ◽  
Review Article ◽  
Chelating Ligands ◽  
Dicarbonyl Compounds ◽  
Synthetic Organic Chemistry ◽  
Material Chemistry ◽  
Recent Developments ◽  
Nitrogen Heterocyclic

: Various diketones such as 1,2-diketones, 1,3-diketones, 1,4-diketones, β-diketones and dicarbonyl compounds are used in the synthesis of core heterocyclic compounds such as pyrazoles, isoxazoles, triazoles and quinolones. They play an important role in synthetic organic chemistry. The diketones and dicarbonyl compounds also act as chelating ligands for the lanthanides and a large number of transition metals in material chemistry. 50% of drugs contain nitrogen heterocyclic compounds, so organic chemists have made efforts for the synthesis of nitrogen-containing heterocyclic compounds. This review article has compiled different methodologies for the synthesis of five- and six-membered nitrogen-containing heterocyclic compounds.

scholarly journals Recent developments in photoredox-catalyzed remote ortho and para C–H bond functionalizations

2020 ◽  
Vol 16 ◽  
pp. 248-280 ◽  
Author(s):  
Rafia Siddiqui ◽  
Rashid Ali
Keyword(s):  
Organic Chemistry ◽  
Total Synthesis ◽  
Research Area ◽  
Photoredox Catalysis ◽  
Organic Transformations ◽  
Research Papers ◽  
Bond Functionalization ◽  
Synthetic Organic Chemistry ◽  
Recent Developments ◽  
The Impact

In recent years, the research area of direct C–H bond functionalizations was growing exponentially not only due to the ubiquity of inert C–H bonds in diverse organic compounds, including bioactive natural and nonnatural products, but also due to its impact on the discovery of pharmaceutical candidates and the total synthesis of intricate natural products. On the other hand, more recently, the field of photoredox catalysis has become an indispensable and unparalleled research topic in modern synthetic organic chemistry for the constructions of challenging bonds, having the foremost scope in academia, pharmacy, and industry. Therefore, the development of green, simpler, and effective methodologies to accomplish direct C–H bond functionalization is well overdue and highly desirable to the scientific community. In this review, we mainly highlight the impact on, and the utility of, photoredox catalysts in inert ortho and para C–H bond functionalizations. Although a surge of research papers, including reviews, demonstrating C–H functionalizations have been published in this vital area of research, to our best knowledge, this is the first review that focuses on ortho and para C–H functionalizations by photoredox catalysis to provide atom- and step-economic organic transformations. We are certain that this review will act as a promoter to highlight the application of photoredox catalysts for the functionalization of inert bonds in the domain of synthetic organic chemistry.

scholarly journals Recent advances and prospects in the palladium-catalyzed cyanation of aryl halides

RSC Advances ◽  
2020 ◽  
Vol 10 (56) ◽  
pp. 33683-33699
Author(s):  
Mohan Neetha ◽  
C. M. A. Afsina ◽  
Thaipparambil Aneeja ◽  
Gopinathan Anilkumar
Keyword(s):  
Organic Chemistry ◽  
Aryl Halides ◽  
Synthetic Organic Chemistry ◽  
Recent Advances ◽  
Aryl Nitriles ◽  
Recent Developments ◽  
Palladium Catalyzed

Aryl nitriles are an inevitable part of synthetic organic chemistry. This review summarizes the recent developments in palladium-catalyzed cyanation of aryl halides from 2012–2020.

scholarly journals A Review on LDH-Smart Functionalization of Anodic Films of Mg Alloys

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 536
Author(s):  
Mosab Kaseem ◽  
Karna Ramachandraiah ◽  
Shakhawat Hossain ◽  
Burak Dikici
Keyword(s):  
Industrial Applications ◽  
Mg Alloys ◽  
Anodic Films ◽  
Electrolytic Oxidation ◽  
Recent Developments ◽  
Plasma Electrolytic ◽  
Co Precipitation ◽  
Corrosive Environments ◽  
Double Hydroxide

This review presents an overview of the recent developments in the synthesis of layered double hydroxide (LDH) on the anodized films of Mg alloys prepared by either conventional anodizing or plasma electrolytic oxidation (PEO) and the applications of the formed composite ceramics as smart chloride traps in corrosive environments. In this work, the main fabrication approaches including co-precipitation, in situ hydrothermal, and an anion exchange reaction are outlined. The unique structure of LDH nanocontainers enables them to intercalate several corrosion inhibitors and release them when required under the action of corrosion-relevant triggers. The influences of different variables, such as type of cations, the concentration of salts, pH, and temperature, immersion time during the formation of LDH/anodic film composites, on the electrochemical response are also highlighted. The correlation between the dissolution rate of PEO coating and the growth rate of the LDH film was discussed. The challenges and future development strategies of LDH/anodic films are also highlighted in terms of industrial applications of these materials.

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