Nitriles as radical acceptors in radical cascade reactions

2021 ◽  
Author(s):  
Kai Sun ◽  
Qi-Yan Lv ◽  
Ying-Wu Lin ◽  
Bing Yu ◽  
Wei-Min He
Keyword(s):  
Cyano Group ◽  
Cascade Reactions ◽  
Radical Acceptor ◽  
Radical Cascade

The application of the cyano group as a radical acceptor in the cascade reactions for the construction of various important heterocycles and carbocycles was summarized.

scholarly journals Cascades, Catalysis and Chiral Ligand Control with SmI2; The Rebirth of a Reagent

2020 ◽  
Vol 74 (1) ◽  
pp. 18-22
Author(s):  
Áron Péter ◽  
David J. Procter
Keyword(s):  
Electron Transfer ◽  
Cascade Reactions ◽  
Single Electron ◽  
Radical Reactions ◽  
Chiral Ligand ◽  
Single Electron Transfer ◽  
Recent Developments ◽  
Radical Cascade

This review focuses on recent developments from our laboratory in the field of radical reactions mediated by the archetypal reductive single electron transfer (SET) reagent, SmI2. Namely, we have expanded the scope of reducible carbonyl moieties to esters and amides and have exploited the resultant ketyl radicals in radical cascade reactions that generate unprecedented scaffolds. Moreover, we have taken the first steps to address the long-standing challenges of catalysis and chiral ligand control associated with the reagent.

Silyl radical initiated radical cascade addition/cyclization: synthesis of silyl functionalized 4H-pyrido[4,3,2-gh]phenanthridin-5(6H)-ones

2018 ◽  
Vol 16 (47) ◽  
pp. 9223-9229 ◽  
Author(s):  
Chen Zhang ◽  
Junxia Pi ◽  
Lei Wang ◽  
Ping Liu ◽  
Peipei Sun
Keyword(s):  
Double Bond ◽  
Cyano Group ◽  
Aromatic Substitution ◽  
Silyl Radical ◽  
Carbon Double Bond ◽  
Homolytic Aromatic Substitution ◽  
Radical Cascade

A cyclization cascade initiated by the addition of a silyl radical to an electron-deficient carbon–carbon double bond of N-arylacrylamides, followed by intramolecular cyano group insertion and homolytic aromatic substitution has been reported.

New Radical Cascade Reactions Incorporating Multiple One-Carbon Radical Synthons:  A Versatile Synthetic Methodology for Vicinal Singly and Doubly Acylated Oxime Ethers

1999 ◽  
Vol 121 (51) ◽  
pp. 12190-12191 ◽  
Author(s):  
Ilhyong Ryu ◽  
Hiroki Kuriyama ◽  
Satoshi Minakata ◽  
Mitsuo Komatsu ◽  
Joo-Yong Yoon ◽  
...  
Keyword(s):  
Cascade Reactions ◽  
Synthetic Methodology ◽  
Radical Cascade

Synthesis of natural quinazolinones and some of their analogues through radical cascade reactions involving N-acylcyanamides

Tetrahedron ◽  
2013 ◽  
Vol 69 (36) ◽  
pp. 7699-7705 ◽  
Author(s):  
Marie-Hélène Larraufie ◽  
Max Malacria ◽  
Christine Courillon ◽  
Cyril Ollivier ◽  
Louis Fensterbank ◽  
...  
Keyword(s):  
Cascade Reactions ◽  
Radical Cascade

Preparation of Fused Polycyclic Vinylcyclopropanes via Radical Cascade Reactions.

ChemInform ◽  
2007 ◽  
Vol 38 (28) ◽  
Author(s):  
Matthew L. Maddess ◽  
Emily Mainetti ◽  
Youssef Harrak ◽  
Celia Brancour ◽  
Priscille Devin ◽  
...  
Keyword(s):  
Cascade Reactions ◽  
Radical Cascade

First Example of Chelation Control during Radical Cascade Reactions of β-Hydroxyester Derivatives

Synlett ◽  
1999 ◽  
Vol 1999 (9) ◽  
pp. 1462-1464 ◽  
Author(s):  
Philippe Renaud ◽  
Laura Andrau ◽  
Kurt Schenk
Keyword(s):  
Cascade Reactions ◽  
Radical Cascade
Sign in / Sign up

Export Citation Format

Share Document