Catalytic asymmetric synthesis of quaternary trifluoromethyl α- to ε-amino acid derivatives via umpolung allylation/2-aza-Cope rearrangement
Keyword(s):
In this study, we developed an efficient Ir-catalyzed cascade umpolung allylation/2-aza-Cope rearrangement for the preparation of a variety of quaternary trifluoromethyl α-ε-amino acids in high yields with excellent enantioselectivities.
2012 ◽
Vol 354
(8)
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pp. 1443-1449
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2009 ◽
Vol 19
(14)
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pp. 3795-3797
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2003 ◽
Vol 79B
(7)
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pp. 181-189
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