A DNAzyme-driven random biped DNA walking nanomachine for ultrasensitive detection of UDG activity

The Analyst ◽  
2021 ◽  
Author(s):  
Li Tan ◽  
Jiangnan Lu ◽  
Xin Wang ◽  
Guang Liu ◽  
Xiaomei Mu ◽  
...  

Highly specific and ultrasensitive detection of Uracil-DNA glycosylase (UDG) activity is of great significance for maintaining genomic integrity and medical research of related diseases. Here, we constructed a random DNA...

ACS Sensors ◽  
2020 ◽  
Vol 5 (6) ◽  
pp. 1615-1623 ◽  
Author(s):  
Xiaolong Chen ◽  
Yawen Wu ◽  
Gaihua Cao ◽  
Xianfeng Wang ◽  
Zhong Ji ◽  
...  

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