Reactivity of N-acyl hydrazone probes with the mammalian proteome

Small molecule probes with distinct reactivities are useful tools for the identification and characterization of protein modifications and function.

Faculty Opinions recommendation of Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1001210.377705 ◽

2006 ◽

Author(s):

Steve Rattigan

Keyword(s):

Type 2 Diabetes ◽

Metabolic Syndrome ◽

Small Molecule ◽

The Metabolic Syndrome ◽

Faculty Opinions recommendation of Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1001210.374806 ◽

2006 ◽

Author(s):

Bruce Kemp

Keyword(s):

Type 2 Diabetes ◽

Metabolic Syndrome ◽

Small Molecule ◽

The Metabolic Syndrome ◽

Faculty Opinions recommendation of Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1283961.751061 ◽

2009 ◽

Author(s):

Marie-France Carlier

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Actin Assembly ◽

Molecule Inhibitor ◽

Identification and characterization of a novel small molecule agonist of lipoprotein lipase by random screening (654.12)

The FASEB Journal ◽

10.1096/fasebj.28.1_supplement.654.12 ◽

2014 ◽

Vol 28 (S1) ◽

Author(s):

Prabodh Sadana ◽

Danielle Aring ◽

Jamie Burke ◽

Werner Geldenhuys

Keyword(s):

Lipoprotein Lipase ◽

Small Molecule ◽

Identification And Characterization ◽

Random Screening

Identification and characterization of benzo[d]oxazol-2(3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111656 ◽

2019 ◽

Vol 182 ◽

pp. 111656 ◽

Cited By ~ 3

Author(s):

Lixin Yang ◽

Yongqing Liu ◽

Minghua Fan ◽

Guiwang Zhu ◽

Hongwei Jin ◽

...

Keyword(s):

Small Molecule ◽

Identification and Characterization of a Small Molecule Antagonist of Human VPAC2 Receptor

Molecular Pharmacology ◽

10.1124/mol.109.060137 ◽

2009 ◽

Vol 77 (1) ◽

pp. 95-101 ◽

Cited By ~ 23

Author(s):

Alan Chu ◽

Jeremy S. Caldwell ◽

Yu Alice Chen

Keyword(s):

Small Molecule ◽

Small Molecule Antagonist ◽

Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders

ACS Medicinal Chemistry Letters ◽

10.1021/acsmedchemlett.7b00153 ◽

2017 ◽

Vol 8 (6) ◽

pp. 618-621 ◽

Cited By ~ 20

Author(s):

David E. Puleo ◽

Kaury Kucera ◽

Henrik M. Hammarén ◽

Daniela Ungureanu ◽

Ana S. Newton ◽

...

Keyword(s):

Small Molecule ◽

Identification and Characterization of Small-Molecule Inhibitors of Lysine Acetyltransferases

Methods in Molecular Biology - Cancer Epigenetics ◽

10.1007/978-1-4939-1804-1_28 ◽

2014 ◽

pp. 539-548

Author(s):

Daiqing Liao

Keyword(s):

Small Molecule ◽

Abstract 1378: Identification and characterization of small molecule inhibitors targeting Eya phosphatase activity for anti-breast cancer therapy

10.1158/1538-7445.am2011-1378 ◽

2011 ◽

Author(s):

Aaron Krueger ◽

Seameen Dehdashti ◽

Noel Southhall ◽

Samarjit Patnaik ◽

Juan Marugan ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Therapy ◽

Phosphatase Activity ◽

Small Molecule ◽

Breast Cancer Therapy ◽

Abstract 1377: Identification and characterization of small molecule inhibitors of the activator protein-1 pathway

10.1158/1538-7445.am2011-1377 ◽

2011 ◽

Author(s):

Nicole R. Miller ◽

Ruili Huang ◽

Menghang Xia

Keyword(s):

Small Molecule ◽

Activator Protein 1 ◽

Activator Protein ◽