Fabrication of the narrow size nano curcuminoids emulsion by combining phase inversion temperature and ultrasonication: preparation and bioactivity

2021 ◽  
Author(s):  
Quang Hieu Tran ◽  
Thuy Thanh Ho ◽  
Tu Thanh Nguyen

A comprehensive study from Curcuma longa to powder nano curcuminoids has been carried out. Combining of both low energy method (Phase Inversion Temperature) and high-energy method (Ultrasonication), a series of...

2014 ◽  
Vol 1060 ◽  
pp. 99-102 ◽  
Author(s):  
Hafiz Mahmood Hasan ◽  
Jiraporn Leanpolchareanchai ◽  
Anchalee Jintapattanakit

Presently, the low energy emulsification method; phase inversion temperature (PIT) method offers a convenient mean of nanoemulsion formation for the incorporation of fragile substances. The aim of the current study was to prepare coconut oil nanoemulsions using cremophor RH 40 as nonionic surfactant in the light of PIT method. The suitable composition of coconut oil, cremophor RH40 and water was investigated by construction of ternary phase diagram. The PIT of system can be adjusted to 75 °C by adding NaCl at the concentration of 6%(w/w). Stable translucent nanoemulsions with particle size in range of 20-100 nm and PDI<0.2 can be formed at the constituent proportions of 5%-30%(w/w), coconut oil, 10%-80%(w/w) cremophor RH40 and 5%-85%(w/w) NaCl solution of 6%(w/w). All formulations were stable for up to 2 months when stored at 4, 30 and 40 °C and protected from light.


2012 ◽  
Vol 44 (11) ◽  
pp. 1077-1081 ◽  
Author(s):  
Kiyoshi Suzuki ◽  
Kohei Nishiyama ◽  
Isao Yamanaka ◽  
Takatoshi Koshiba ◽  
Shuzaemon Satoh

Langmuir ◽  
2004 ◽  
Vol 20 (16) ◽  
pp. 6594-6598 ◽  
Author(s):  
Paqui Izquierdo ◽  
Jordi Esquena ◽  
Tharward F. Tadros ◽  
Joseph C. Dederen ◽  
Jin Feng ◽  
...  

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