Discovery of 13,15-nor-Polycyclic Polyprenylated Acylphloroglucinols from Hypericum longistylum with Anti-Inflammatory Activity

2022 ◽  
Author(s):  
Zhengyi Shi ◽  
Hong Hu ◽  
Yi Guo ◽  
Yulin Duan ◽  
Yeting Zhang ◽  
...  
Keyword(s):  
Ring System ◽  
Inflammatory Activity ◽  
Anti Inflammatory

Spihyperglucinols A (1) and B (2), the first 13,15-nor-polycyclic polyprenylated acylphloroglucinols (PPAPs) featuring a 7/6/5 tricyclic ring system based on an unexpected bicyclo[3.2.2]nonane core, along with three new congeners, spihyperglucinols...

scholarly journals Streptoglycerides E–H, Unsaturated Polyketides from the Marine-Derived Bacterium Streptomyces specialis and Their Anti-Inflammatory Activity

Marine Drugs ◽  
2022 ◽  
Vol 20 (1) ◽  
pp. 44
Author(s):  
Hee Jae Shin ◽  
Chang-Su Heo ◽  
Cao Van Anh ◽  
Yeo Dae Yoon ◽  
Jong Soon Kang
Keyword(s):  
Spectroscopic Data ◽  
2D Nmr ◽  
Ring System ◽  
Membered Ring ◽  
Inflammatory Activity ◽  
Raw 264.7 Cells ◽  
No Production ◽  
Nmr Data ◽  
Ic50 Values ◽  
Anti Inflammatory

Four new streptoglycerides E–H (1–4), with a rare 6/5/5/-membered ring system, were isolated from a marine-derived actinomycete Streptomyces specialis. The structures of 1–4 were elucidated by detailed analysis of HRESIMS, 1D and 2D NMR data and ECD spectra as well as comparison of their spectroscopic data with those reported in literature. Compounds 1–4 showed significant anti-inflammatory activity by inhibiting lipopolysaccharide (LPS)-induced nitric oxide (NO) production in Raw 264.7 cells with IC50 values ranging from 3.5 to 10.9 µM. Especially, 2 suppressed mRNA expression levels of iNOS and IL-6 without cytotoxicity.

Anti-platelet and anti-inflammatory activity of Plumbago zeylanicus (Pz), Phyllanthus emblica (Pe) and their combination

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
DA Uchil ◽  
SK Kamat ◽  
SS Menon ◽  
AM Scindia ◽  
GK Dang ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Phyllanthus Emblica ◽  
Anti Inflammatory

A new flavonol with anti-inflammatory activity from Boldoa purpurascens Cav.

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
DM González Mosquera ◽  
A Kilonda ◽  
S Toppet ◽  
F Compernolle ◽  
W Dehaen ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Anti Inflammatory

Isolation characterization and anti-inflammatory activity of Rhaphiostylis beninensis Planch. Ex Benth (Icacinaceae)

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
J Ofeimun ◽  
B Ayinde ◽  
I Igbe ◽  
MI Choudhary ◽  
I Husain ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Anti Inflammatory

Cytotoxic and anti-inflammatory activity of diarylbutane lignans from the bark of Bursera ariensis

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
ME Acevedo-Quiroz ◽  
LP Álvarez Berber ◽  
S Marquina Bahena ◽  
A León Cabrera ◽  
A Cardoso Taketa ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Anti Inflammatory

Antiproliferative and anti-inflammatory activity of fraction containing terpenes from Croton campestris A. St.-Hil. (Euphorbiaceae)

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
P Monteiro ◽  
D Vendramini-Costa ◽  
AL Ruiz ◽  
MA Foglio ◽  
JE Carvalho
Keyword(s):  
Inflammatory Activity ◽  
Anti Inflammatory

Study on the anti-inflammatory activity from Zizyphus jujuba Mill

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
BM Lee ◽  
JS Lee ◽  
JA Kim ◽  
BS Min
Keyword(s):  
Inflammatory Activity ◽  
Zizyphus Jujuba ◽  
Anti Inflammatory
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