scholarly journals Transition metal-catalyzed synthesis of spirooxindoles

RSC Advances ◽  
2021 ◽  
Vol 11 (13) ◽  
pp. 7146-7179
Author(s):  
P. V. Saranya ◽  
Mohan Neetha ◽  
Thaipparambil Aneeja ◽  
Gopinathan Anilkumar
Keyword(s):  
Transition Metal ◽  
Transition Metals ◽  
Antimicrobial Agents ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Spirooxindoles are used as anticancer-, antiviral-, antimicrobial agents etc. The use of transition metals as catalysts for the synthesis of spirooxindoles is advancing rapidly. Here, we focus on recent advances in transition metal-catalyzed synthesis of spirooxindoles.

scholarly journals Recent advances on the transition-metal-catalyzed synthesis of imidazopyridines: an updated coverage

2019 ◽  
Vol 15 ◽  
pp. 1612-1704 ◽  
Author(s):  
Gagandeep Kour Reen ◽  
Ashok Kumar ◽  
Pratibha Sharma
Keyword(s):  
Transition Metal ◽  
Transition Metals ◽  
Method Development ◽  
Deep Understanding ◽  
Catalyst Loading ◽  
Coupling Reactions ◽  
Reaction Conditions ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

A comprehensive account of recent advances in the synthesis of imidazopyridines, assisted through transition-metal-catalyzed multicomponent reactions, C–H activation/functionalization and coupling reactions are highlighted in this review article. The basic illustration of this review comprises of schemes with concise account of explanatory text. The schemes depict the reaction conditions along with a quick look into the mechanism involved to render a deep understanding of the catalytic role. At some instances optimizations of certain features have been illustrated through tables, i.e., selectivity of catalyst, loading of the catalyst and percentage yield with different substrates. Each of the reported examples has been rigorously analyzed for reacting substrates, reaction conditions and transition metals used as the catalyst. This review will be helpful to the chemists in understanding the challenges associated with the reported methods as well as the future possibilities, both in the choice of substrates and catalysts. This review would be quite appealing to a wider range of organic chemists in academia and industrial R&D sectors working in the field of heterocyclic syntheses. In a nutshell, this review will be a guiding torch to envisage: (i) the role of various transition metals in the domain dedicated towards method development and (ii) for the modifications needed thereof in the R&D sector.

scholarly journals Recent advances in transition-metal-catalyzed intermolecular carbomagnesiation and carbozincation

2013 ◽  
Vol 9 ◽  
pp. 278-302 ◽  
Author(s):  
Kei Murakami ◽  
Hideki Yorimitsu
Keyword(s):  
Transition Metal ◽  
Transition Metals ◽  
Recent Advances ◽  
Group 3 ◽  
Directing Group ◽  
Transition Metal Catalyzed ◽  
Electron Withdrawing Group ◽  
Group 2 ◽  
Metal Catalyzed ◽  
Organozinc Reagents

Carbomagnesiation and carbozincation reactions are efficient and direct routes to prepare complex and stereodefined organomagnesium and organozinc reagents. However, carbon–carbon unsaturated bonds are generally unreactive toward organomagnesium and organozinc reagents. Thus, transition metals were employed to accomplish the carbometalation involving wide varieties of substrates and reagents. Recent advances of transition-metal-catalyzed carbomagnesiation and carbozincation reactions are reviewed in this article. The contents are separated into five sections: carbomagnesiation and carbozincation of (1) alkynes bearing an electron-withdrawing group; (2) alkynes bearing a directing group; (3) strained cyclopropenes; (4) unactivated alkynes or alkenes; and (5) substrates that have two carbon–carbon unsaturated bonds (allenes, dienes, enynes, or diynes).

Chelation-assisted transition metal-catalysed C–H chalcogenylations

2020 ◽  
Vol 7 (8) ◽  
pp. 1022-1060 ◽  
Author(s):  
Wenbo Ma ◽  
Nikolaos Kaplaneris ◽  
Xinyue Fang ◽  
Linghui Gu ◽  
Ruhuai Mei ◽  
...  
Keyword(s):  
Transition Metal ◽  
Recent Advances ◽  
Site Selectivity ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

This review summarizes recent advances in C–S and C–Se formations via transition metal-catalyzed C–H functionalization utilizing directing groups to control the site-selectivity.

Recent advances in transition metal-catalyzed asymmetric electrocatalysis

2021 ◽  
Vol 444 ◽  
pp. 214065
Author(s):  
Priyanka Chakraborty ◽  
Rajib Mandal ◽  
Nidhi Garg ◽  
Basker Sundararaju
Keyword(s):  
Transition Metal ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Biaryl Synthesis via Electrooxidative Transition Metal Catalyzed C−H Activation

Synthesis ◽  
2021 ◽  
Author(s):  
Jonas Felix Goebel ◽  
Zhongyi Zeng ◽  
Lukas Goossen
Keyword(s):  
Transition Metal ◽  
Recent Advances ◽  
Biaryl Synthesis ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

The use of electricity as an inexpensive and waste-free oxidant opens up new opportunities for the development of sustainable C–H functionalization reactions. Herein we summarize recent advances in the synthesis of biaryls through electrooxidative processes involving transition metal catalyzed ortho-directed C−H activation. A particular focus is set on electrooxidative C−H/C−M couplings and dehydrogenative couplings.

Amide-Directed Reactions of Small Carbocycles

2021 ◽  
Vol 25 ◽  
Author(s):  
Pavel M. Yamanushkin ◽  
Marina Rubina ◽  
Michael Rubin
Keyword(s):  
Transition Metal ◽  
Transition Metals ◽  
Nucleophilic Addition ◽  
Addition Reactions ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

: The topic of this review is the amide-directed functionalization of strained carbocycles — specifically, unsaturated or saturated three- and four-membered rings. The following approaches are discussed: a) directed carbometallation and hydrometallation of cyclopropenes catalyzed by transition metals; b) directed metal-templated nucleophilic addition reactions; c) directed C-H functionalization, including transition metal-catalyzed C-H-activation reactions; and d) directed radical additions.

Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation

2017 ◽  
Vol 4 (7) ◽  
pp. 1435-1467 ◽  
Author(s):  
Wenbo Ma ◽  
Parthasarathy Gandeepan ◽  
Jie Li ◽  
Lutz Ackermann
Keyword(s):  
Transition Metal ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Recent advances in transition-metal catalyzed positional-selective alkenylations via twofold C–H activation directed by removable or traceless directing groups are reviewed.

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