scholarly journals Synthesis and cytotoxicity against tumor cells of pincer N-heterocyclic ligands and their transition metal complexes

RSC Advances ◽  
2021 ◽  
Vol 11 (55) ◽  
pp. 34742-34753
Author(s):  
Afaf Oulmidi ◽  
Smaail Radi ◽  
Abderrazak Idir ◽  
Abdelmajid Zyad ◽  
Imad Kabach ◽  
...  

The complexes: [CoL2](ClO4)2 (1), [FeL2](ClO4)2 (2), [NiL2](ClO4)2 (3) and [MnLCl2] (4), with L = diethyl-1,1′-(pyridine-2,6-diyl)bis(5-methyl-1H-pyrazole-3-carboxylate), were synthesized and fully characterized.

RSC Advances ◽  
2017 ◽  
Vol 7 (29) ◽  
pp. 17923-17933 ◽  
Author(s):  
Bi-Qun Zou ◽  
Xing Lu ◽  
Qi-Pin Qin ◽  
Yu-Xia Bai ◽  
Ye Zhang ◽  
...  

Complex 1 was more selective for MGC80-3 tumor cells versus normal cells (HL-7702). Importantly, 1 triggered MGC80-3 cells apoptosis via a mitochondrial dysfunction pathway.


2016 ◽  
Vol 45 (5) ◽  
pp. 2261-2272 ◽  
Author(s):  
Mohamed Shaker S. Adam ◽  
Markus K. Kindermann ◽  
Peter G. Jones ◽  
Joachim W. Heinicke

Novel bicyclic P,N-heterocyclic ligands and the first P- and P,N-coordinated LM(0)(CO)5, LRh(COD)Cl, (LPd(All)Cl)2PdCl2 and (LPdCl2)2 transition metal complexes thereof are presented.


1969 ◽  
Vol 23 ◽  
pp. 1503-1513 ◽  
Author(s):  
Britta Mynster Dahl ◽  
Otto Dahl ◽  
Terence Painter ◽  
Arne Haug ◽  
Per-Erik Werner ◽  
...  

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