scholarly journals Correlation of Fc Receptor Expression of Monocytes with Clearance Function by Macrophages in Systemic Lupus erythematosus

1998 ◽  
Vol 48 (3) ◽  
pp. 307-311 ◽  
Author(s):  
Seres ◽  
Csipo ◽  
Kiss ◽  
Szegedi ◽  
Kavai
Lupus ◽  
2021 ◽  
pp. 096120332110450
Author(s):  
Ramdani Yanis ◽  
Cécile Bergua ◽  
Barbet Christelle ◽  
François Maillot ◽  
Adrien Bigot ◽  
...  

The neonatal Fc receptor (FcRn) is a ubiquitously expressed protein historically involved in IgG and albumin recycling. Recent data suggest an involvement in the pathophysiology of antibody-mediated autoimmune diseases. Among them, systemic lupus erythematosus (SLE) implies clinical and biological abnormalities of innate and adaptive circulating immune cells, potentially involving newly described functions of FcRn. In this study, FcRn expression was assessed by flow cytometry in peripheral blood leukocytes of 41 SLE patients with either active or inactive disease and 32 healthy donors. FcRn expression in B cells, natural killer cells, and T cells of SLE patients was statistically lower as compared to healthy donors. Conversely, FcRn level was statistically higher in non-classical monocyte subpopulations (CD14+CD16+ monocytes) of SLE patients versus healthy donors providing an interesting perspective to further explore its role in SLE pathophysiology.


Author(s):  
Yanis Ramdani ◽  
Cécile Bergua ◽  
Christelle Barbet ◽  
François Maillot ◽  
Adrien Bigot ◽  
...  

2009 ◽  
Vol 37 (1) ◽  
pp. 191-196 ◽  
Author(s):  
Chen Mao ◽  
Haifeng Pan ◽  
Qing Chen ◽  
Xiwen Wang ◽  
Dongqing Ye ◽  
...  

1982 ◽  
Vol 25 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Max I. Hamburger ◽  
Thomas J. Lawley ◽  
Robert P. Kimberly ◽  
Paul H. Plotz ◽  
Michael M. Frank

1995 ◽  
Vol 38 (12) ◽  
pp. 1832-1836 ◽  
Author(s):  
Ashley J. Duits ◽  
Hendrika Bootsma ◽  
Ronald H. W. M. Derksen ◽  
Peter E. Spronk ◽  
Louis Kater ◽  
...  

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