scholarly journals Key indicators for the monitoring and evaluation of control programmes of human African trypanosomiasis due to Trypanosoma brucei gambiense

1998 ◽  
Vol 3 (6) ◽  
pp. 474-481 ◽  
Author(s):  
Bouchet ◽  
Legros ◽  
Lee
Keyword(s):  
Trypanosoma Brucei ◽  
Human African Trypanosomiasis ◽  
Monitoring And Evaluation ◽  
African Trypanosomiasis ◽  
Trypanosoma Brucei Gambiense ◽  
Control Programmes ◽  
Key Indicators

Human African trypanosomiasis

2020 ◽  
pp. 1451-1459
Author(s):  
Reto Brun ◽  
Johannes Blum
Keyword(s):  
Trypanosoma Brucei ◽  
Human African Trypanosomiasis ◽  
Specific Treatment ◽  
Protozoan Parasite ◽  
Control Measures ◽  
Tsetse Flies ◽  
African Trypanosomiasis ◽  
Control Programmes ◽  
The 1960S ◽  
Stage 1

Human African trypanosomiasis (sleeping sickness) is caused by subspecies of the protozoan parasite Trypanosoma brucei. The disease is restricted to tropical Africa where it is transmitted by the bite of infected tsetse flies (Glossina spp.). Control programmes in the 1960s were very effective, but subsequent relaxation of control measures led to recurrence of epidemic proportions in the 1980s and 1990s. Control is now being regained. Untreated human African trypanosomiasis is almost invariably fatal. Specific treatment depends on the trypanosome subspecies and the stage of the disease. Drugs used for stage 1 include pentamidine and suramin, and for stage 2 include melarsoprol, eflornithine, and nifurtimox, but regimens are not standardized, and treatment is difficult and dangerous; all of the drugs used have many side effects, some potentially lethal.

scholarly journals Host age and time of exposure in Trypanosoma brucei gambiense Human African Trypanosomiasis

2002 ◽  
Vol 7 (5) ◽  
pp. 429-434 ◽  
Author(s):  
A. Garcia ◽  
V. Jamonneau ◽  
B. Sane ◽  
F. Fournet ◽  
P. N'Guessan ◽  
...  
Keyword(s):  
Trypanosoma Brucei ◽  
Human African Trypanosomiasis ◽  
Host Age ◽  
African Trypanosomiasis ◽  
Trypanosoma Brucei Gambiense
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