Estimation of heritability for hip dysplasia in German Shepherd Dogs in Finland

2000 ◽  
Vol 117 (3) ◽  
pp. 97-103 ◽  
Author(s):  
M. Leppänen ◽  
K. Mäki ◽  
J. Juga ◽  
H. Saloniemi
2011 ◽  
Vol 128 (3) ◽  
pp. 219-229 ◽  
Author(s):  
K.F. Stock ◽  
S. Klein ◽  
B. Tellhelm ◽  
O. Distl

2008 ◽  
Vol 49 (3) ◽  
pp. 243-248 ◽  
Author(s):  
ANTJE WIGGER ◽  
BERND TELLHELM ◽  
MARTIN KRAMER ◽  
HEIKE RUDORF

1995 ◽  
Vol 08 (02) ◽  
pp. 114-117 ◽  
Author(s):  
J. S. Madsen ◽  
E. Svalastoga

SummaryPresently, the diagnosis of hip dysplasia is based on a single pelvic radiographic examination of the dog at the age of 12 to 24 months. However, by this method, only a static appearance of the coxofemoral joint is evaluated. The purpose of our study was to diagnose hip dysplasia in young dogs and consequently, we included a radiographic evaluation of the dynamic appearance of the coxofemoral joint.A stress-radiographic examination was applied to 23 German Shepherd Dogs at the age of six and 12 months to obtain maximal reduction and maximal dislocation of the coxofemoral joint. Finally, at the age of 12 months, the hips were examined radiographically using the conventional criteria for hip dysplasia.At the age of six months, dogs with hip dysplasia showed significantly greater joint laxity and lateral dislocation of the femoral head than normal dogs. However, some predysplastic dogs, with lateral dislocation of the femoral head, developed normal hips and would be approved for breeding. Based on these findings, we conclude that stress-radiographic examinations of young dogs provide important, hitherto unrecognized, information of relevance in the future screening programmes to reduce the incidence of hip dysplasia.A stress-radiographic examination of young dogs provides important, hitherto unrecognized, information of relevance in the future screening programmes to reduce the incidence of hip dysplasia.


2018 ◽  
Vol 74 (2) ◽  
pp. 6069-2018
Author(s):  
PAULINA KRZEMIŃSKA ◽  
MACIEJ GOGULSKI ◽  
ROMAN ALEKSIEWICZ ◽  
MAREK ŚWITOŃSKI

Canine hip dysplasia is a complex skeletal malformation caused by genetic and environmental factors. The prevalence of hip dysplasia in different canine breeds ranges widely, from 1% (for Whippet and Borzoi) to over 70% (for Bulldog and Pug). These differences indicate the presence of genetic variants predisposing to or preventing this disorder in gene pools of particular breeds. The importance of genetic factors is also confirmed by a high coefficient of heritability (h2) of canine hip dysplasia, which for most breeds oscillates around 0.5 – 0.6. Application of modern genomic methods, that is, mainly genome scanning (based previously on microsatellite markers and currently on SNP microarrays) has led in recent years to the identification of potential genetic markers associated with this disorder. Such studies were carried out mostly in two breeds: Labrador retriever and German shepherd. Some of the markers were found in the vicinity of genes involved in skeletal development. Following these achievements, the use of some markers has been suggested for early risk diagnosis of hip dysplasia. This shows that molecular testing is becoming important for not only monogenic, but also polygenic canine diseases and disorders. Identification of genetic markers associated with predisposition to hip dysplasia offers an opportunity for an early risk evaluation of this disorder (prior to its first signs). Moreover, it facilitates effective breeding selection aimed at eradicating undesirable genetic variants from the gene pool of a given breed..


2019 ◽  
Vol 171 ◽  
pp. 104745
Author(s):  
Adriane Yumi Babá ◽  
Carlos Antonio Lopes de Oliveira ◽  
Grazyella Massako Yoshida ◽  
Marcus Túlio Cavalcante Costa ◽  
Leonir Bueno Ribeiro ◽  
...  

2000 ◽  
Vol 117 (2) ◽  
pp. 97-103 ◽  
Author(s):  
M. Leppaänen ◽  
K. Maäki ◽  
J. Juga ◽  
H. Saloniemi

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