CASE REPORT: A rare association of primary biliary cirrhosis and systemic lupus erythematosus and review of the literature

2002 ◽  
Vol 14 (5) ◽  
pp. 431-435 ◽  
Author(s):  
Shamsul Islam ◽  
John Riordan ◽  
Jennifer Mcdonald
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Primary Biliary Cirrhosis ◽  
Lupus Erythematosus ◽  
Biliary Cirrhosis ◽  
Review Of The Literature ◽  
Systemic Lupus ◽  
Rare Association

scholarly journals Anti-MDA5 Antibody Dermatomyositis Overlap with Systemic Lupus Erythematosus: A Case Report and Review of the Literature

2016 ◽  
Vol 10 (1) ◽  
pp. 122-128 ◽  
Author(s):  
Emily C. Milam ◽  
Jacobo Futran ◽  
Andrew G. Franks Jr.
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lupus Erythematosus ◽  
Clinical Phenotype ◽  
Review Of The Literature ◽  
Systemic Lupus ◽  
American College Of Rheumatology ◽  
Clinical Presentations

Background: Dermatomyositis (DM) is an autoimmune connective tissue disease that primarily targets the muscle, skin, and lungs. Many patients have autoantibodies that correspond to distinct clinical phenotypes. Melanoma differentiation-associated gene 5 (anti-MDA5) antibody, a specific antibody that targets the melanoma differentiation-associated gene 5 (MDA5), has been reported in DM cases and is significant for a distinct cutaneous presentation and rapidly progressive interstitial lung disease. Objective: Herein, we describe a patient with DM with a positive anti-MDA5 antibody and characteristic clinical phenotype, who subsequently developed coexisting systemic lupus erythematosus (SLE). A diagnosis of SLE was supported by his clinical phenotype, positive serologies, hypocomplementemia, and progression to glomerulonephritis and lupus cerebritis, features of which fulfilled the American College of Rheumatology criteria for SLE. Conclusion: DM is known to overlap with other autoimmune diseases, including SLE, and coexistence can lead to a wide variety of clinical presentations. SLE overlapping with anti-MDA5 positive DM may present with distinct clinical features.

scholarly journals Multifocal osteonecrosis in systemic lupus erythematosus: case report and review of the literature

2013 ◽  
Vol 2013 (apr16 1) ◽  
pp. bcr2013008980-bcr2013008980 ◽  
Author(s):  
L. D. Fajardo-Hermosillo ◽  
L. Lopez-Lopez ◽  
A. Nadal ◽  
L. M. Vila
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Lupus Erythematosus ◽  
Review Of The Literature ◽  
Systemic Lupus ◽  
Systemic Lupus Erythematosus Case
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