Development of Design Methods of a Centrifugal Blood Pump with In Vitro Tests, Flow Visualization, and Computational Fluid Dynamics: Results inHemolysis Tests

1998 ◽  
Vol 22 (5) ◽  
pp. 393-398 ◽  
Author(s):  
Koki Takiura ◽  
Toru Masuzawa ◽  
Seiko Endo ◽  
Yoshinari Wakisaka ◽  
Eisuke Tatsumi ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Flow Visualization ◽  
Design Methods ◽  
Blood Pump ◽  
In Vitro Tests ◽  
Centrifugal Blood Pump

Effect of blade curvature on the hemolytic and hydraulic characteristics of a centrifugal blood pump

2018 ◽  
Vol 41 (11) ◽  
pp. 730-737 ◽  
Author(s):  
Caglar Ozturk ◽  
I Basar Aka ◽  
Ismail Lazoglu
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
In Silico ◽  
Estimation Method ◽  
Computational Method ◽  
Blood Pump ◽  
Centrifugal Blood Pump ◽  
Pump Design ◽  
Straight Blade

Aims: Impeller design has a significant impact on the overall performance of a blood pump. In this study, the effect of the blade curvature was investigated by performing in silico and in vitro studies on a recently developed centrifugal blood pump. Methods: A computational fluid dynamics study was performed for the flow rates of 3–5 L/min at 2000 r/min. The computational fluid dynamics model was also applied on the US Food and Drug Administration (FDA) benchmark blood pump to validate our computational method. The relative hemolysis index was calculated with the Eulerian hemolysis estimation method for five impellers with the wrap angles ranging from 0° to 240°. Hydraulic experiments were conducted for the validation of computational fluid dynamics results. In addition, the curved-blade impeller (120°) and the straight-blade impeller (0°) were evaluated with in vitro hemolysis tests using human blood. Results: The wrap angle of 120° provided the best hydraulic and hemolytic performance. Pump achieved the physiologic operating pressures and flows with 85–115 mmHg at 2.5–5.9 L/min. Compared to the straight-blade impeller, the 120° model reduces the relative hemolysis index and the plasma-free hemoglobin near 72.8% and 56.7%, respectively. Comparison of in silico and in vitro results indicated the similar trend to the blade curvature. Conclusion: Introducing a blade curvature enhanced the hydrodynamic and hemolytic performance compared to the straight-blade configuration for the investigated centrifugal blood pump. The findings of this study provide new insights into centrifugal blood pump design by examining the influence of the blade curvature.

Computational Fluid Dynamics Analysis of the Pediatric Tiny Centrifugal Blood Pump (TinyPump)

2006 ◽  
Vol 30 (5) ◽  
pp. 392-399 ◽  
Author(s):  
Kazuyuki Kido ◽  
Hideo Hoshi ◽  
Nobuo Watanabe ◽  
Hiroyuki Kataoka ◽  
Katsuhiro Ohuchi ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Blood Pump ◽  
Dynamics Analysis ◽  
Centrifugal Blood Pump ◽  
Computational Fluid Dynamics Analysis

Computational Fluid Dynamics Investigation of a Centrifugal Blood Pump

2008 ◽  
Vol 32 (4) ◽  
pp. 342-348 ◽  
Author(s):  
Daniel Legendre ◽  
Pedro Antunes ◽  
Eduardo Bock ◽  
Aron Andrade ◽  
José F. Biscegli ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Blood Pump ◽  
Centrifugal Blood Pump

Computational Fluid Dynamics Analysis of a Centrifugal Blood Pump with Washout Holes

2000 ◽  
Vol 24 (8) ◽  
pp. 648-652 ◽  
Author(s):  
Yuki Tsukamoto ◽  
Kazuyuki Ito ◽  
Toshio Sawairi ◽  
Yoshiaki Konishi ◽  
Takashi Yamane ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Blood Pump ◽  
Dynamics Analysis ◽  
Centrifugal Blood Pump ◽  
Computational Fluid Dynamics Analysis

A Compact Centrifugal Blood Pump for Extracorporeal Circulation: Design and Performance

1987 ◽  
Vol 109 (3) ◽  
pp. 272-278 ◽  
Author(s):  
Shinobu Tanaka ◽  
Shuzo Yamamoto ◽  
Ken-ichi Yamakoshi ◽  
Akira Kamiya
Keyword(s):  
Thrombus Formation ◽  
Animal Experiments ◽  
Left Ventricular ◽  
Blood Pump ◽  
Assisted Circulation ◽  
In Vitro Tests ◽  
Outer Diameter ◽  
Centrifugal Blood Pump ◽  
And Performance

A new compact centrifugal blood pump driven by a miniature DC servomotor has been designed for use for short-term extra corporeal and cardiac-assisted circulation. The impeller of the pump was connected directly to the motor by using a simple-gear coupling. The shaft for the impeller was sealed from blood by both a V-ring and a seal bearing. Either pulsatile or nonpusatile flow was produced by controlling the current supply to the motor. The pump characteristics and the degree of hemolysis were evaluated with regard to the configuration of the impeller with a 38-mm outer diameter in vitro tests; the impeller having the blade angles at the inlet of 20 deg and at the outlet of 50 deg was the most appropriate as a blood pump. The performance in an operation, hemolysis and thrombus formation in the pump were assessed by a left ventricular bypass experiment in dogs. It was suggested by this study that this prototype pump appears promising for use not only in animal experiments but also in clinical application.

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