scholarly journals The CoBiS Linked Open Data Project and Portal

2018 ◽  
Vol 186 ◽  
pp. 12013 ◽  
Author(s):  
Luisa Schiavone ◽  
Federico Morando ◽  

The CoBiS is a network formed by 65 libraries. The project is a pilot for Piedmont that is aiming to provide the Committee with an infrastructure for LOD publishing, thus creating a triplification pipeline designed to be easy to automate and replicate. This is being realized with open source technologies, such as the RML mapping language or the JARQL tool that uses Linked Data to describe the conversion of XML, JSON or tabular data into RDF. The first challenge consisted in making possible the dialog of heterogeneous data sources, coming from four different library software (Clavis, Erasmo, SBNWeb and BIBLIOWin 5.0web) and different types of data (bibliographic, multimedia, and archival). The information contained in the catalogs is progressively interlinked with external data sources, such as Wikidata, VIAF, LoC and BNF authority files, Wikipedia and the Dizionario Biografico degli Italiani. Partners of the CoBiS LOD Project are: National Institute for Astrophysics (INAF), Turin Academy of Sciences, Olivetti Historical Archives Association, Alpine Club National Library, Deputazione Subalpina di Storia Patria, National Institute for Metrological Research (INRIM). The technical realization of the project is entrusted to Synapta, and it is partially sponsored by Piedmont Region.

2016 ◽  
Vol 53 ◽  
pp. 172-191 ◽  
Author(s):  
Eduardo M. Eisman ◽  
María Navarro ◽  
Juan Luis Castro

iScience ◽  
2021 ◽  
pp. 103298
Author(s):  
Anca Flavia Savulescu ◽  
Emmanuel Bouilhol ◽  
Nicolas Beaume ◽  
Macha Nikolski

2015 ◽  
Author(s):  
Lisa M. Breckels ◽  
Sean Holden ◽  
David Wojnar ◽  
Claire M. Mulvey ◽  
Andy Christoforou ◽  
...  

AbstractSub-cellular localisation of proteins is an essential post-translational regulatory mechanism that can be assayed using high-throughput mass spectrometry (MS). These MS-based spatial proteomics experiments enable us to pinpoint the sub-cellular distribution of thousands of proteins in a specific system under controlled conditions. Recent advances in high-throughput MS methods have yielded a plethora of experimental spatial proteomics data for the cell biology community. Yet, there are many third-party data sources, such as immunofluorescence microscopy or protein annotations and sequences, which represent a rich and vast source of complementary information. We present a unique transfer learning classification framework that utilises a nearest-neighbour or support vector machine system, to integrate heterogeneous data sources to considerably improve on the quantity and quality of sub-cellular protein assignment. We demonstrate the utility of our algorithms through evaluation of five experimental datasets, from four different species in conjunction with four different auxiliary data sources to classify proteins to tens of sub-cellular compartments with high generalisation accuracy. We further apply the method to an experiment on pluripotent mouse embryonic stem cells to classify a set of previously unknown proteins, and validate our findings against a recent high resolution map of the mouse stem cell proteome. The methodology is distributed as part of the open-source Bioconductor pRoloc suite for spatial proteomics data analysis.AbbreviationsLOPITLocalisation of Organelle Proteins by Isotope TaggingPCPProtein Correlation ProfilingMLMachine learningTLTransfer learningSVMSupport vector machinePCAPrincipal component analysisGOGene OntologyCCCellular compartmentiTRAQIsobaric tags for relative and absolute quantitationTMTTandem mass tagsMSMass spectrometry


2018 ◽  
Vol 42 (1) ◽  
pp. 39-61 ◽  
Author(s):  
Marko Gulić ◽  
Marin Vuković

Ontology matching plays an important role in the integration of heterogeneous data sources that are described by ontologies. In order to determine correspondences between ontologies, a set of matchers can be used. After the execution of these matchers and the aggregation of the results obtained by these matchers, a final alignment method is executed in order to select appropriate correspondences between entities of compared ontologies. The final alignment method is an important part of the ontology matching process because it directly determines the output result of this process. In this paper we improve our iterative final alignment method by introducing an automatic adjustment of final alignment threshold as well as a new rule for determining false correspondences with similarity values greater than adjusted threshold. An evaluation of the method is performed on the test ontologies of the OAEI evaluation contest and a comparison with other final alignment methods is given.


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