scholarly journals Association Between Long-term Oral Contraceptive Use and Risk of Crohn’s Disease Complications in a Nationwide Study

2016 ◽  
Vol 150 (7) ◽  
pp. 1561-1567.e1 ◽  
Author(s):  
Hamed Khalili ◽  
Fredrik Granath ◽  
Karin E. Smedby ◽  
Anders Ekbom ◽  
Martin Neovius ◽  
...  
1993 ◽  
Vol 38 (9) ◽  
pp. 1596-1600 ◽  
Author(s):  
Bettina Katschinski ◽  
Dagmar Fingerle ◽  
Bernward Scherbaum ◽  
Harald Goebell

2001 ◽  
Vol 120 (5) ◽  
pp. A627-A627 ◽  
Author(s):  
S CAMPBELL ◽  
W WATSON ◽  
B WALKER ◽  
R PARK ◽  
A BEATTIE ◽  
...  

1998 ◽  
Vol 114 ◽  
pp. A956
Author(s):  
J. Cosnes ◽  
F. Carbonnel ◽  
F. Carrat ◽  
L. Beaugerie ◽  
J.P. Gendre

1998 ◽  
Vol 114 (6) ◽  
pp. 1143-1150 ◽  
Author(s):  
Antje Timmer ◽  
Lloyd R. Sutherland ◽  
Francois Martin

2001 ◽  
Vol 120 (5) ◽  
pp. A627
Author(s):  
Stewart Campbell ◽  
Walter S. Watson ◽  
Barbara J. Walker ◽  
Richard Park ◽  
Alistair D. Beattie ◽  
...  

1992 ◽  
Vol 37 (9) ◽  
pp. 1377-1382 ◽  
Author(s):  
L. R. Sutherland ◽  
S. Ramcharan ◽  
H. Bryant ◽  
G. Fick

Gut ◽  
1999 ◽  
Vol 45 (2) ◽  
pp. 218-222 ◽  
Author(s):  
J Cosnes ◽  
F Carbonnel ◽  
F Carrat ◽  
L Beaugerie ◽  
J-P Gendre

BACKGROUNDWomen with Crohn’s disease are usually advised not to take oral contraceptives, but, unlike smoking, there is no clear association between current oral contraceptive use and more severe disease.AIMTo assess the effect of oral contraceptive use on the clinical course of Crohn’s disease.PATIENTS331 women, aged 16–50 years, with Crohn’s disease and Crohn’s disease activity index <200, were enrolled consecutively during a one year period. Patients were classified at inclusion as oral contraceptive users or non-users and smokers or non-smokers.METHODSA prospective 12–18 month cohort study was used. The main outcome measures were flare up rate and time to flare up.RESULTSIn total, 134 women used oral contraceptives, in most cases low oestrogen formulations. During the study period, 61 oral contraceptive users (46%) developed a flare up, compared with 85 non-users (43%). The hazard ratio for oral contraceptive use was 1.11 (95% confidence interval 0.80 to 1.55). Variables associated with flare up were smoking status, recently active disease, baseline Crohn’s disease activity index, and presence of anoperineal lesions. The same results were obtained when the analysis was restricted to patients eligible for a relapse prevention trial.CONCLUSIONUnlike smoking, oral contraceptives have no effect on Crohn’s disease activity.


2008 ◽  
Vol 16 (6) ◽  
pp. 372-376 ◽  
Author(s):  
M. Isabel Fiel ◽  
Albert Min ◽  
Michael A. Gerber ◽  
Bridget Faire ◽  
Myron Schwartz ◽  
...  

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