The Role of FDG-PET and Whole-Body MRI in High Grade Bone Sarcomas With Particular Focus on Osteosarcoma

Author(s):  
Arianna Farina ◽  
Chiara Gasperini ◽  
Maria Pilar Aparisi Gómez ◽  
Alberto Bazzocchi ◽  
Stefano Fanti ◽  
...  
2013 ◽  
Vol 94 (2) ◽  
pp. 169-183 ◽  
Author(s):  
R. Duvauferrier ◽  
M. Valence ◽  
S. Patrat-Delon ◽  
E. Brillet ◽  
E. Niederberger ◽  
...  

2007 ◽  
Vol 48 (8) ◽  
pp. 1237-1244 ◽  
Author(s):  
H.-S. Jeong ◽  
M. K. Chung ◽  
Y.-I. Son ◽  
J. Y. Choi ◽  
H. J. Kim ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Pet Ct ◽  
18F Fdg ◽  

2014 ◽  
Vol 24 (5) ◽  
pp. 1153-1165 ◽  
Author(s):  
Annemieke S. Littooij ◽  
Thomas C. Kwee ◽  
Ignasi Barber ◽  
Claudio Granata ◽  
Malou A. Vermoolen ◽  
...  

ISRN Oncology ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-11
Author(s):  
G. P. Bandopadhyaya ◽  
Priyanka Gupta ◽  
Archana Singh ◽  
Jaya Shukla ◽  
S. Rastogi ◽  
...  

To evaluate the role of 99mTc-DMSA (V) and [18F]FDG PET-CT in management of patients with osteosarcoma, 22 patients were included in our study. All patients underwent both 99mTc-DMSA (V) and whole-body [18F]FDG PET-CT scans within an interval of 1 week. 555–740 MBq of 99mTc-DMSA (V) was injected i.v. the whole-body planar, SPECT images of primary site and chest were performed after 3-4 hours. [18F]FDG PET-CT images were obtained 60 minutes after i.v. injection of 370 MBq of F-18 FDG. Both FDG PET-CT (mean SUVmax = 7.1) and DMSA (V) scans showed abnormal uptake at primary site in all the 22 patients (100% sensitivity for both). Whole-body PET-CT detected metastasis in 11 pts (lung mets in 10 and lung + bone mets in 1 patient). Whole-body planar DMSA (V) and SPECT detected bone metastasis in one patient, lung mets in 7 patients and LN in 1 patient. HRCT of chest confirmed lung mets in 10 patients and inflammatory lesion in one patient. 7 patients positive for mets on DMSA (V) scan had higher uptake in lung lesions as compared to FDG uptake on PET-CT. Three patients who did not show any DMSA uptake had subcentimeter lung nodule. Resuts of both 99mTc-DMSA (V) (whole-body planar and SPECT imaging) and [18F]FDG PET-CT were comparable in evaluation of primary site lesions and metastatic lesions greater than 1 cm. Though 99mTc-DMSA (V) had higher uptake in the lesions as compared to [18F]FDG PET-CT, the only advantage [18F]FDG PET-CT had was that it could also detect subcentimeter lesions.


2009 ◽  
Vol 192 (4) ◽  
pp. 1012-1020 ◽  
Author(s):  
Roberto C. Domingues ◽  
Michel P. Carneiro ◽  
Fernanda Cristina Rueda Lopes ◽  
Romeu C. Domingues ◽  
Lea Mirian Barbosa da Fonseca ◽  
...  

2013 ◽  
Vol 38 (7) ◽  
pp. e290-e296 ◽  
Author(s):  
Andrei Iagaru ◽  
Phillip Young ◽  
Erik Mittra ◽  
David W. Dick ◽  
Robert Herfkens ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Alessandro Stecco ◽  
Francesco Buemi ◽  
Martina Quagliozzi ◽  
Mariangela Lombardi ◽  
Alberto Santagostino ◽  
...  

Background. The purpose of this study was to compare the accuracy of whole-body MRI with diffusion-weighted sequences (WB-DW-MRI) with that of18F-FDG-PET/CT in the staging of patients with primary gastrointestinal lymphoma.Methods. This retrospective study involved 17 untreated patients with primary abdominal gastrointestinal lymphoma. All patients underwent18F-FDG-PET/CT and WB-DW-MRI. Histopathology findings or at least 6 months of clinical and radiological follow-up was the gold standard. The Musshoff-modified Ann Arbor system was used for staging, and diagnostic accuracy was evaluated on a per-node basis.Results. WB-DW-MRI exhibited 100% sensitivity, 96.3% specificity, and 96.1% and 100% positive and negative predictive values (PPV and NPV), respectively. The sensitivity, specificity, and PPV and NPV of PET/CT were 95.9%, 100%, and 100% and 96.4%, respectively. There were no statistically significant differences between the two techniquesp=0.05. The weighted kappa agreement statistics with a 95% confidence interval were 0.97 (0.95–0.99) between the two MRI readers and 0.87 (0.82–0.92) between the two methods.Conclusions. WB-DW-MRI appears to have a comparable diagnostic value to18F-FDG-PET/CT in staging patients with gastrointestinal lymphoma.


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