scholarly journals Liver cell proliferation requires methionine adenosyltransferase 2A mRNA up-regulation

Hepatology ◽  
2002 ◽  
Vol 35 (6) ◽  
pp. 1381-1391 ◽  
Author(s):  
Covadonga Pañeda ◽  
Itziar Gorospe ◽  
Blanca Herrera ◽  
Toshikazu Nakamura ◽  
Isabel Fabregat ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Liver Cell ◽  
Methionine Adenosyltransferase

Evidence for and Characterization of a Liver Cell Proliferation Factor from Blood Plasma of Partially Hepatectomized Rats

1980 ◽  
Vol 12 (03) ◽  
pp. 94-96 ◽  
Author(s):  
M. Goldberg ◽  
W. Strecker ◽  
D. Feeny ◽  
G. Ruhenstroth-Bauer
Keyword(s):  
Cell Proliferation ◽  
Blood Plasma ◽  
Liver Cell

scholarly journals Blocking swelling‐activated chloride current inhibits mouse liver cell proliferation

2001 ◽  
Vol 532 (3) ◽  
pp. 661-672 ◽  
Author(s):  
Robert Wondergem ◽  
Wei Gong ◽  
Scott H. Monen ◽  
Sean N. Dooley ◽  
Joel L. Gonce ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Liver Cell ◽  
Mouse Liver ◽  
Chloride Current ◽  
Mouse Liver Cell

Interactive effects of methyl-deficiency and dietary restrictionon liver cell proliferation and telomerase activity in Fischer 344 rats pretreated with aflatoxin B1

2000 ◽  
Vol 152 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Ming W Chou ◽  
Marina V Mikhailova ◽  
Jasyl Nichols ◽  
Lionel A Poirier ◽  
Alan Warbritton ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Liver Cell ◽  
Aflatoxin B1 ◽  
Telomerase Activity ◽  
Interactive Effects ◽  
Fischer 344 Rats ◽  
Fischer 344

Myostatin inhibits proliferation and insulin-stimulated glucose uptake in mouse liver cells

2014 ◽  
Vol 92 (3) ◽  
pp. 226-234 ◽  
Author(s):  
Rani Watts ◽  
Mostafa Ghozlan ◽  
Curtis C. Hughey ◽  
Virginia L. Johnsen ◽  
Jane Shearer ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cell Proliferation ◽  
Glucose Uptake ◽  
Liver Cell ◽  
Noncoding Rna ◽  
Muscle Growth ◽  
Liver Cells ◽  
Negative Regulator ◽  
Kinase Substrate ◽  
Akt Phosphorylation

Although myostatin functions primarily as a negative regulator of skeletal muscle growth and development, accumulating biological and epidemiological evidence indicates an important contributing role in liver disease. In this study, we demonstrate that myostatin suppresses the proliferation of mouse Hepa-1c1c7 murine-derived liver cells (50%; p < 0.001) in part by reducing the expression of the cyclins and cyclin-dependent kinases that elicit G1-S phase transition of the cell cycle (p < 0.001). Furthermore, real-time PCR-based quantification of the long noncoding RNA metastasis associated lung adenocarcinoma transcript 1 (Malat1), recently identified as a myostatin-responsive transcript in skeletal muscle, revealed a significant downregulation (25% and 50%, respectively; p < 0.05) in the livers of myostatin-treated mice and liver cells. The importance of Malat1 in liver cell proliferation was confirmed via arrested liver cell proliferation (p < 0.05) in response to partial Malat1 siRNA-mediated knockdown. Myostatin also significantly blunted insulin-stimulated glucose uptake and Akt phosphorylation in liver cells while increasing the phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS), a protein that is essential for cancer cell proliferation and insulin-stimulated glucose transport. Together, these findings reveal a plausible mechanism by which circulating myostatin contributes to the diminished regenerative capacity of the liver and diseases characterized by liver insulin resistance.

Influence of vinyl chloride monomer (VCM) and As2O3 on rat liver cell proliferation after partial hepatectomy

1980 ◽  
Vol 97 (1) ◽  
pp. 41-50 ◽  
Author(s):  
K. Norpoth ◽  
D. Gottschalk ◽  
I. Gottschalk ◽  
U. Witting ◽  
H. Thomas ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Partial Hepatectomy ◽  
Vinyl Chloride ◽  
Rat Liver ◽  
Liver Cell ◽  
Vinyl Chloride Monomer

Furan-induced liver cell proliferation and apoptosis in female B6C3F1 mice

Toxicology ◽  
1997 ◽  
Vol 118 (2-3) ◽  
pp. 195-204 ◽  
Author(s):  
Ronny Fransson-steen ◽  
Thomas L. Goldsworthy ◽  
Gregory L. Kedderis ◽  
robert R. Maronpot
Keyword(s):  
Cell Proliferation ◽  
Liver Cell ◽  
Proliferation And Apoptosis ◽  
B6c3f1 Mice

109 Numerical Simulation of Liver Cell Proliferation with Angiogenesis

2015 ◽  
Vol 2015.68 (0) ◽  
pp. 17-18
Author(s):  
Hiroto TANAKA ◽  
Katsuya NAGAYAMA ◽  
Nana SHIRAKIGAWA ◽  
Hiroyuki IJIMA
Keyword(s):  
Numerical Simulation ◽  
Cell Proliferation ◽  
Liver Cell

scholarly journals Identification of a natural mutant of HBV X protein truncated 27 amino acids at the COOH terminal and its effect on liver cell proliferation

2008 ◽  
Vol 29 (4) ◽  
pp. 473-480 ◽  
Author(s):  
Hang ZHANG ◽  
Chang-liang SHAN ◽  
Nan LI ◽  
Xuan ZHANG ◽  
Xue-zhi ZHANG ◽  
...  
Keyword(s):  
Amino Acids ◽  
Cell Proliferation ◽  
Liver Cell ◽  
X Protein

Effect on the human liver cell proliferation after caveolin-1 gene knock-down

2008 ◽  
Vol 32 (3) ◽  
pp. S45-S45
Author(s):  
Gang Ren ◽  
Ying Liu ◽  
Xiao Min Wang ◽  
Wei Zou
Keyword(s):  
Cell Proliferation ◽  
Liver Cell ◽  
Human Liver ◽  
Caveolin 1 ◽  
Knock Down ◽  
Human Liver Cell
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