Therapie des akuten viralen Katzenschnupfens

2019 ◽  
Vol 47 (02) ◽  
pp. 98-109
Author(s):  
Michèle Bergmann ◽  
Anne Ballin ◽  
Bianka Schulz ◽  
René Dörfelt ◽  
Katrin Hartmann

ZusammenfassungDie Haupterreger des Katzenschnupfens, das feline Herpesvirus-1 (FHV-1) und das feline Calicivirus (FCV), sind in Katzenpopulationen weit verbreitet, vor allem in Haushalten mit vielen Katzen auf engem Raum. Katzen mit schweren klinischen Symptomen müssen meist stationär behandelt werden. Eine intensive symptomatische Therapie wirkt sich positiv auf den Heilungsverlauf aus. Der Einsatz antiviraler Medikamente bei Katzen ist limitiert, da viele der Substanzen unwirksam oder bei systemischer Gabe toxisch sind. Antivirale Medikamente werden daher vor allem lokal zur Therapie FHV-1-assoziierter Augenveränderungen eingesetzt. Famciclovir ist jedoch als wirksames Virostatikum zur systemischen Therapie bei Katzen mit FHV-1-bedingten Symptomen geeignet. Gegen FCV sind nur wenige antivirale Medikamente verfügbar. Der Einsatz von Immunglobulinen führte in einer kontrollierten Studie bei Katzen mit FHV-1- und/oder FCV-Infektion zu einer signifikant schnelleren Besserung der Symptome eines akuten Katzenschnupfens.

2016 ◽  
Vol 19 (4) ◽  
pp. 461-469 ◽  
Author(s):  
Mireia Fernandez ◽  
Edgar G Manzanilla ◽  
Albert Lloret ◽  
Marta León ◽  
Jean-Christophe Thibault

Objectives Our objective was to perform the first multicentric study in Spain to evaluate the prevalence of feline herpesvirus-1 (FHV-1), feline calicivirus (FCV), Chlamydophila felis and Mycoplasma felis in cats with upper respiratory tract disease (URTD), conjunctivitis and/or gingivostomatitis (GS) compared with control cats; and to evaluate risk factors for these clinical conditions. Methods Conjunctival and oropharyngeal swabs were collected and a questionnaire regarding signalment, lifestyle, vaccination history and clinical signs was obtained for each cat. Swabs were tested for each pathogen by real-time PCR. Results The study population consisted of 358 cats, including 98 control cats. Among the 260 diseased cats, 127 cats presented with URTD, 149 cats had conjunctivitis, 154 cats were suffering GS; many cats presented more than one clinical condition. The prevalence observed of FHV-1, FCV, C felis and M felis was, respectively, 28.3%, 48.0%, 20.5% and 46.5% in cats with URTD; 24.2%, 43.6%, 19.5% and 38.3% in cats with conjunctivitis; and 15.6%, 58.4%, 9.1% and 37.7% in cats with GS. Prevalences in the control group were 6.1%, 15.3%, 2.0% and 20.4%, respectively. Coinfections were common among all groups of cats. Risk factors were identified for all groups. FHV-1, FCV and C felis were associated with URTD and conjunctivitis. FCV was strongly associated with GS. M felis was present in a high percentage of the population in all groups, but its role in these clinical conditions remains uncertain. Vaccination was protective for URTD and GS but not for conjunctivitis. Conclusions and relevance This epidemiological study describes, for the first time, prevalence for FHV-1, FCV, C felis and M felis in Spain. In general, the prevalences found are similar to those reported in other countries. Factors associated with disease expression were also identified, which are relevant for practitioners.


2005 ◽  
Vol 7 (6) ◽  
pp. 325-331 ◽  
Author(s):  
Bodil Ström Holst ◽  
Louise T. Berndtsson ◽  
Lena Englund

Feline calicivirus (FCV) could be isolated from four cats (2.6%) and feline herpesvirus-1 (FHV) from none of 152 clinically healthy cats from 22 Swedish breeding catteries. These cats had all previously shown signs of respiratory tract disease or conjunctivitis, although several years ago. The results suggest that carriers of FCV and FHV were uncommon in Swedish breeding catteries studied. Prevalence rates in other European countries and North America are usually higher, especially of FCV. The lower prevalence rates in our study might be explained by test group selection, differences in factors such as management, environment, or genetic constitution of the cats, or by sample handling. It was concluded that the presence of an FCV shedder in the cattery does not mean that all cats in the group are infected, but special measures are recommended to avoid infection of susceptible cats.


2019 ◽  
Vol 35 (3) ◽  
pp. 131-138
Author(s):  
Seval Bilge Dağalp ◽  
Fırat Doğan ◽  
Touraj Aligholipour Farzani ◽  
Ali Rıza Babaoğlu ◽  
Gülizar Acar Kırmızı ◽  
...  

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