scholarly journals Malignant Peripheral Nerve Sheath Tumor of the Infraorbital Nerve

2016 ◽  
Vol 9 (2) ◽  
pp. 170-174
Author(s):  
JoséLuis D'Addino ◽  
Laura Piccoletti ◽  
MaríaMercedes Pigni ◽  
Maria José Rodriguez Arenas de Gordon
Keyword(s):  
Peripheral Nerve ◽  
Chronic Atrial Fibrillation ◽  
Radical Resection ◽  
Infraorbital Nerve ◽  
Malignant Schwannoma ◽  
Ocular Motility ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
History Of

The objective of this study is to report a large, rare, and ulcerative infiltrated skin lesion. Its diagnosis, therapeutic management, and progress are described. The patient is a 78-year-old white man, who presented with a 12-month ulcerative perforated lesion that had affected and infiltrated the skin, with easy bleeding. He had a history of hypertension, although controlled, was a 40-year smoker, had chronic atrial fibrillation, diabetes, and microangiopathy. During the consultation, the patient also presented with ocular obstruction due to an inability to open the eye. He mentioned having reduced vision. The computed tomography scan showed upper maxilla osteolysis without eye involvement. We underwent a radical resection in which upper maxilla and the anterior orbital margin were included. We used a Becker-type flap that allowed us to rebuild the cheek and to complete a modified neck dissection. Progress was favorable; the patient recovered ocular motility and his vision improved to 20/200. The final biopsy result was “malignant peripheral nerve sheath tumor, malignant schwannoma.” Malignant schwannoma of the peripheral nerve is extremely rare. The total resection and reconstruction being completed in one surgery represented a challenge due to the difficulty in obtaining tissues in addition to the necessity of an oncological resection.

Epithelioid variant of malignant peripheral nerve sheath tumor (malignant schwannoma) of the urinary bladder

1999 ◽  
Vol 3 (5) ◽  
pp. 304-308 ◽  
Author(s):  
Isam A. Eltoum ◽  
R. Jemison Moore ◽  
William Cook ◽  
D. Ralph Crowe ◽  
William H. Rodgers ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Peripheral Nerve ◽  
Malignant Schwannoma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Epithelioid Variant

scholarly journals RECURRENCE OF MALIGNANT PERIPHERAL NERVE SHEATH TUMOR

2021 ◽  
Vol 7 (4) ◽  
pp. 145-148
Author(s):  
Alin Istodor ◽  
Ovidiu Ardelean ◽  
Carmen Rădulescu ◽  
Octavian Mazilu
Keyword(s):  
Case Report ◽  
Peripheral Nerve ◽  
Ct Scan ◽  
Pelvic Pain ◽  
Malignant Schwannoma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Pelvic Region ◽  
Nerve Sheath ◽  
Short Period

Peripheral nerve sheath tumor (PNST) is known as a benign tumor called Schwannomas, developed from the Schwann cells that produce myelin and collagen, and can occur in a wide variety of locations. In some cases, it can take a malignant turn and grow as a pelvic mass known as malignant peripheral nerve sheath tumor (MPNST), malignant schwannoma, malignant neurofibroma, malignant mesenchynoma and neurogenic sarcoma. Our case report presents a female patient presenting dysuria and pelvic pain. The clinical examination revealed a palpable mass in the lower abdomen. The computer tomography (CT) scan of the abdomen and pelvic region showed a tumor mass that was in contact with the nearby organs, but not infiltrating them. After the surgery, histopathology confirmed the MPNST proliferation. A month after, the patient returned for a follow-up and presenting pelvic pain. The CT scan of the abdomen and pelvic region showed a tumoral mass compressing the nearby organs, but not infiltrating them. The patient was referred to oncology board for palliative treatment. The particularity of this case report is the short period of time recurrence of the MPNST, rather than metastases. The most important treatment for MPNSTs remains surgery, trying to achieve negative margins. However, there have been reported two cases of unresectable MPSNT with partial remission to chemo- and radiotherapy.  

Peripheral Nerve Sheath Tumor of the Vagus Nerve in a Dog

2016 ◽  
Vol 52 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Fui Yap ◽  
Kathryn Pratschke
Keyword(s):  
Peripheral Nerve ◽  
Vagus Nerve ◽  
Cervical Region ◽  
Nerve Sheath Tumor ◽  
Computed Tomography Scan ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
History Of ◽  
Tomography Scan ◽  
Exploratory Surgery

A peripheral nerve sheath tumor was diagnosed in a female, neutered Labrador retriever with a 6 mo history of coughing, retching, ptyalism, and left-sided Horner's syndrome. Computed tomography scan of the neck revealed a mass lesion between the carotid artery and esophagus in the mid-cervical region. Exploratory surgery was performed and an 18 cm section of thickened vagus nerve was excised. Histopathological findings and immunochemistry staining confirmed a malignant peripheral nerve sheath tumor. The tumor showed microscopic signs of malignancy, but there were no macroscopic signs of local extension or distant metastasis. This report documents a peripheral nerve sheath tumor of rare origin in dogs.

scholarly journals Intrathoracic malignant peripheral nerve sheath tumor with poor outcome: a case report

2010 ◽  
Vol 10 (4) ◽  
pp. 328-330 ◽  
Author(s):  
Violeta Kolarov ◽  
Jelena Stanić ◽  
Živka Eri ◽  
Biljana Zvezdin ◽  
Marija Kojičić ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Sheath Tumor ◽  
Lethal Outcome ◽  
Body Mass Loss ◽  
Large Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Progressive Dyspnea ◽  
History Of ◽  
The Right

We report a case of intrathoracic malignant peripheral nerve sheath tumor in a 65-year old woman revealed after a few-month history of progressive dyspnea, appetite and body mass loss. The chest magnetic resonance (MR) examination revealed the presence of a large tumor occupying the mediastinum and a major portion of the right hemithorax. The diagnostic tumor sample was obtained by parasternal biopsy in local anesthesia. The surgical resection of the tumor could not be performed due to its excessive size, intrathoracic involvement and bad respiratory reserves of a patient. The chemotherapy and irradiation were performed as palliative measures. The lethal outcome appeared 10 months after the diagnosis was established.

Recurrent Malignant Peripheral Nerve Sheath Tumor Presenting As an Asymptomatic Intravenous Thrombus Extending to the Heart: A Case Report

2021 ◽  
Author(s):  
Toru Hirozane ◽  
Robert Nakayama ◽  
Sayaka Yamaguchi ◽  
Tomoaki Mori ◽  
Naofumi Asano ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Radial Nerve ◽  
Subclavian Vein ◽  
Tumor Thrombus ◽  
Venous Invasion ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
History Of ◽  
The Right

Abstract Background: Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma mainly treated via surgical resection. Herein, we report a case of MPNST wherein a massive tumor thrombus extended to the major veins and heart.Case presentation: A 39-year-old female with a history of neurofibromatosis type 1 developed MPNST from the right radial nerve. In addition to adjuvant chemotherapy, she underwent wide tumor resection and concomitant radial nerve resection, followed by postoperative radiotherapy. Histological evaluation revealed marked venous invasion. The 2-year follow-up CT revealed an asymptomatic recurrent tumor thrombus extending from the right subclavian vein to the heart. An urgent life-saving operation was performed to ligate the base of the right subclavian vein and remove the entire intravenous thrombus that extended to the right ventricle. The remaining tumor in the right subclavian vein increased in size 3 months after thrombectomy. After confirming the absence of any metastatic lesions, the patient underwent extended forequarter amputation to achieve surgical remission. One year later, a new metastasis to the right diaphragm was safely resected. The patient remains alive without any evidence of disease 2 years after the extended forequarter amputation. Conclusions: In cases of a previous history of microscopic venous invasion, recurrence can occur as a massive tumor thrombus that extends to the great vessels.

scholarly journals Recurrent malignant peripheral nerve sheath tumor presenting as an asymptomatic intravenous thrombus extending to the heart: a case report

2022 ◽  
Vol 20 (1) ◽  
Author(s):  
Toru Hirozane ◽  
Robert Nakayama ◽  
Sayaka Yamaguchi ◽  
Tomoaki Mori ◽  
Naofumi Asano ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Radial Nerve ◽  
Subclavian Vein ◽  
Tumor Thrombus ◽  
Venous Invasion ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
History Of ◽  
The Right

Abstract Background Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma mainly treated via surgical resection. Herein, we report a case of MPNST wherein a massive tumor thrombus extended to the major veins and heart. Case presentation A 39-year-old female with a history of neurofibromatosis type 1 developed MPNST from the right radial nerve. In addition to adjuvant chemotherapy, she underwent wide tumor resection and concomitant radial nerve resection, followed by postoperative radiotherapy. Histological evaluation revealed marked venous invasion. The 2-year follow-up CT revealed an asymptomatic recurrent tumor thrombus extending from the right subclavian vein to the heart. An urgent life-saving operation was performed to ligate the base of the right subclavian vein and remove the entire intravenous thrombus that extended to the right ventricle. The remaining tumor in the right subclavian vein increased in size 3 months after thrombectomy. After confirming the absence of any metastatic lesions, the patient underwent extended forequarter amputation to achieve surgical remission. One year later, a new metastasis to the right diaphragm was safely resected. The patient remains alive without any evidence of disease 2 years after the extended forequarter amputation. Conclusions In cases of a previous history of microscopic venous invasion, recurrence can occur as a massive tumor thrombus that extends to the great vessels.

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