Ten Years after the International Committee of Medical Journal Editors’ Clinical Trial Registration Initiative, One Quarter of Phase 3 Pediatric Epilepsy Clinical Trials Still Remain Unpublished: A Cross-Sectional Analysis

2016 ◽  
Vol 47 (S 01) ◽  
Author(s):  
A. Lampert ◽  
G. Hoffmann ◽  
M. Ries
2004 ◽  
Vol 141 (6) ◽  
pp. 477 ◽  
Author(s):  
Catherine De Angelis ◽  
Jeffrey M. Drazen ◽  
Frank A. Frizelle ◽  
Charlotte Haug ◽  
John Hoey ◽  
...  

The Lancet ◽  
2004 ◽  
Vol 364 (9438) ◽  
pp. 911-912 ◽  
Author(s):  
Catherine De Angelis ◽  
Jeffrey M Drazen ◽  
Frank A Frizelle ◽  
Charlotte Haug ◽  
John Hoey ◽  
...  

2014 ◽  
Vol 94 (1) ◽  
pp. 83-90 ◽  
Author(s):  
Abraham Samuel Babu ◽  
Sundar Kumar Veluswamy ◽  
Pratiksha Tilak Rao ◽  
Arun G. Maiya

Background Clinical trial registration has become an important part of editorial policies of various biomedical journals, including a few physical therapy journals. However, the extent to which editorial boards enforce the need for trial registration varies across journals. Objective The purpose of this study was to identify editorial policies and reporting of trial registration details in MEDLINE-indexed English-language physical therapy journals. Design This study was carried out using a cross-sectional design. Methods Editorial policies on trial registration of MEDLINE-indexed member journals of the International Society of Physiotherapy Journal Editors (ISPJE) (Journal of Geriatric Physical Therapy, Journal of Hand Therapy, Journal of Neurologic Physical Therapy, Journal of Orthopaedic and Sports Physical Therapy, Journal of Physiotherapy [formerly Australian Journal of Physiotherapy], Journal of Science and Medicine in Sport, Manual Therapy, Physical Therapy, Physical Therapy in Sport, Physiotherapy, Physiotherapy Research International, Physiotherapy Theory and Practice, and Revista Brasileira de Fisioterapia) were reviewed in April 2013. Full texts of reports of clinical trials published in these journals between January 1, 2008, and December 31, 2012, were independently assessed for information on trial registration. Results Among the 13 journals, 8 recommended trial registration, and 6 emphasized prospective trial registration. As of April 2013, 4,618 articles were published between January 2008 and December 2012, of which 9% (417) were clinical trials and 29% (121/417) of these reported trial registration details. A positive trend in reporting of trial registration was observed from 2008 to 2012. Limitations The study was limited to MEDLINE-indexed ISPJE member journals. Conclusions Editorial policies on trial registration of physical therapy journals and a rising trend toward reporting of trial registration details indicate a positive momentum toward trial registration. Physical therapy journal editors need to show greater commitment to prospective trial registration to make it a rule rather than an option.


2004 ◽  
Vol 351 (12) ◽  
pp. 1250-1251 ◽  
Author(s):  
Catherine De Angelis ◽  
Jeffrey M. Drazen ◽  
Frank A. Frizelle ◽  
Charlotte Haug ◽  
John Hoey ◽  
...  

2015 ◽  
Vol 134 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Carolina Gomes Freitas ◽  
Thomas Fernando Coelho Pesavento ◽  
Maurício Reis Pedrosa ◽  
Rachel Riera ◽  
Maria Regina Torloni

CONTEXT AND OBJECTIVE: Clinical trial registration is a prerequisite for publication in respected scientific journals. Recent Brazilian regulations also require registration of some clinical trials in the Brazilian Clinical Trials Registry (ReBEC) but there is little information available about practical issues involved in the registration process. This article discusses the importance of clinical trial registration and the practical issues involved in this process. DESIGN AND SETTING: Descriptive study conducted by researchers within a postgraduate program at a public university in São Paulo, Brazil. METHODS: Information was obtained from clinical trial registry platforms, article reference lists and websites (last search: September 2014) on the following topics: definition of a clinical trial, history, purpose and importance of registry platforms, the information that should be registered and the registration process. RESULTS: Clinical trial registration aims to avoid publication bias and is required by Brazilian journals indexed in LILACS and SciELO and by journals affiliated to the International Committee of Medical Journal Editors (ICMJE). Recent Brazilian regulations require that all clinical trials (phases I to IV) involving new drugs to be marketed in this country must be registered in ReBEC. The pros and cons of using different clinical trial registration platforms are discussed. CONCLUSIONS: Clinical trial registration is important and various mechanisms to enforce its implementation now exist. Researchers should take into account national regulations and publication requirements when choosing the platform on which they will register their trial.


2016 ◽  
Vol 26 (1) ◽  
pp. 2 ◽  
Author(s):  
Darren B Taichman ◽  
Joyce Backus ◽  
Christopher Baethge ◽  
Howard Bauchner ◽  
Peter W De Leeuw ◽  
...  

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