Potassium Carbonate Promoted C–N Coupling Reaction between Benzamides and Aryl Iodides

Synthesis ◽  
2017 ◽  
Vol 50 (05) ◽  
pp. 1090-1096
Author(s):  
Songlin Zhang ◽  
Fei Huang ◽  
San Wu ◽  
Weiye Hu
Keyword(s):  
Transition Metal ◽  
Potassium Carbonate ◽  
Efficient Method ◽  
Coupling Reaction ◽  
Metal Catalyst ◽  
Transition Metal Catalyst ◽  
Aryl Iodides

A practical and efficient method for N-arylation of benz­amides promoted by potassium carbonate in the presence of DMEDA was developed. The reaction was carried out without addition of any transition-metal catalyst to afford a variety of N-arylated products in moderate to good yields (up to 97%).

Potassium carbonate-mediated tandem C–S and C–N coupling reaction for the synthesis of phenothiazines under transition-metal-free and ligand-free conditions

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24257-24260 ◽  
Author(s):  
San Wu ◽  
Wei-Ye Hu ◽  
Song-Lin Zhang
Keyword(s):  
Transition Metal ◽  
Potassium Carbonate ◽  
Coupling Reaction ◽  
Metal Catalyst ◽  
Phenothiazine Derivatives ◽  
Transition Metal Catalyst ◽  
Metal Free ◽  
Efficient Approach ◽  
Ligand Free

A potassium carbonate-mediated tandem coupling reaction for the synthesis of phenothiazines is described. This protocol affords an efficient approach for the construction of phenothiazine derivatives without the need for addition of transition-metal catalyst or ligand.

scholarly journals Transition Metal Catalyst Free Cross-Coupling Reaction of Tertiary Propargylic Alcohols with Hetero-Areneboronic Acids

2021 ◽  
Author(s):  
Jian-Fei Bai ◽  
Jianbo Tang ◽  
Xiaolong Gao ◽  
Zhi-Jiang Jiang ◽  
Zhanghua Gao
Keyword(s):  
Transition Metal ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Catalyst ◽  
Transition Metal Catalyst ◽  
Propargylic Alcohols ◽  
Catalyst Free ◽  
Cross Coupling Reaction ◽  
Reaction Proceeds ◽  
Acid Catalyzed

We report a perfluorophenylboronic acid catalyzed cross coupling reaction of tertiary propargylic alcohols and hetero-areneboronic acids for valuable benzo[b]thiophene and cyclopenta[a]indene derivates. This coupling reaction proceeds efficiently with a wide array of substrates scope in up to 89% yield and excellent regioselectivity. A significant advantage of our protocol is the transition metal catalyst free and mild conditions needed. This strategy provides direct and facile access to medicinally important benzo[b]thiophene and cyclopenta[a]indene scaffold containing a quaternary carbon center.

scholarly journals Transition Metal Catalyst Free Cross-Coupling Reaction of Tertiary Propargylic Alcohols with Hetero-Areneboronic Acids

2022 ◽  
Author(s):  
Jian-Fei Bai ◽  
Jianbo Tang ◽  
Xiaolong Gao ◽  
Zhi-Jiang Jiang ◽  
Jia Chen ◽  
...  
Keyword(s):  
Transition Metal ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Catalyst ◽  
Transition Metal Catalyst ◽  
Propargylic Alcohols ◽  
Catalyst Free ◽  
Cross Coupling Reaction ◽  
Reaction Proceeds ◽  
Acid Catalyzed

We report a perfluorophenylboronic acid catalyzed cross coupling reaction of tertiary propargylic alcohols and hetero-areneboronic acids for valuable benzo[b]thiophene and cyclopenta[a]indene derivates. This coupling reaction proceeds efficiently with a wide array of substrates scope in up to 89% yield and excellent regioselectivity. A significant advantage of our protocol is the transition metal catalyst free and mild conditions needed. This strategy provides direct and facile access to medicinally important benzo[b]thiophene and cyclopenta[a]indene scaffold containing a quaternary carbon center.

scholarly journals Transition Metal Catalyst Free Cross-Coupling Reaction of Tertiary Propargylic Alcohols with Hetero-Areneboronic Acids

2021 ◽  
Author(s):  
Jian-Fei Bai ◽  
Jianbo Tang ◽  
Xiaolong Gao ◽  
Zhi-Jiang Jiang ◽  
Zhanghua Gao
Keyword(s):  
Transition Metal ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Metal Catalyst ◽  
Transition Metal Catalyst ◽  
Propargylic Alcohols ◽  
Catalyst Free ◽  
Cross Coupling Reaction ◽  
Reaction Proceeds ◽  
Acid Catalyzed

We report a perfluorophenylboronic acid catalyzed cross coupling reaction of tertiary propargylic alcohols and hetero-areneboronic acids for valuable benzo[b]thiophene and cyclopenta[a]indene derivates. This coupling reaction proceeds efficiently with a wide array of substrates scope in up to 89% yield and excellent regioselectivity. A significant advantage of our protocol is the transition metal catalyst free and mild conditions needed. This strategy provides direct and facile access to medicinally important benzo[b]thiophene and cyclopenta[a]indene scaffold containing a quaternary carbon center.

Synthesis of 6-phenylbenzo[h]quinolines via photoinduced dehydrogenative annulation of (E)-2-phenyl-3-styrylpyridines

2021 ◽  
Vol 19 (39) ◽  
pp. 8554-8558
Author(s):  
Lixin Niu ◽  
Yun He ◽  
Jin Xi ◽  
Tao Wang ◽  
Yong Liang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Efficient Method ◽  
Metal Catalyst ◽  
Reaction Conditions ◽  
Transition Metal Catalyst ◽  
Simple Operation ◽  
Catalyst Free ◽  
Free Process

A efficient method for the synthesis of 6-phenylbenzo[h]quinolines 2 has been developed. This strategy has the prominent advantages of simple operation, mild reaction conditions, high atom efficiency, and transition-metal/catalyst-free process.

COx-free hydrogen production via ammonia decomposition over mesoporous Co/Al2O3 catalysts with highly dispersed Co species synthesized by a facile method

2021 ◽  
Author(s):  
Yingqiu Gu ◽  
Di Xu ◽  
Yun Huang ◽  
Zhouyang Long ◽  
Guojian Chen
Keyword(s):  
Fuel Cells ◽  
Hydrogen Production ◽  
Transition Metal ◽  
Transition Metals ◽  
Ammonia Decomposition ◽  
Metal Catalyst ◽  
Facile Synthesis ◽  
Transition Metal Catalyst ◽  
Highly Dispersed ◽  
Free Hydrogen

Transition metals have been considered as potential catalysts for ammonia decomposition to produce COx-free hydrogen for fuel cells. However, the facile synthesis of transition metal catalyst with small size active...

scholarly journals Transition Metal Catalyst‐Free, Base‐Promoted 1,2‐Additions of Polyfluorophenylboronates to Aldehydes and Ketones

2021 ◽  
Author(s):  
Zhiqiang Liu ◽  
Goutam Kumar Kole ◽  
Yudha P. Budiman ◽  
Ya-Ming Tian ◽  
Alexandra Friedrich ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Catalyst ◽  
Free Base ◽  
Transition Metal Catalyst ◽  
Catalyst Free ◽  
Aldehydes And Ketones
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