Intermolecular Trapping of Alkoxyl Radicals with Alkenes: A New Route to Ether Synthesis
Keyword(s):
Alkoxyl radicals are highly reactive species which rapidly react by hydrogen atom transfer (HAT) or β-fragmentation to afford a carbon-centered radical. We discuss herein how these RO· radicals can be efficiently trapped in an intermolecular manner by styrene derivatives when they are generated by photoredox catalysis from the corresponding N-alkoxypyridinium salts. This allows for the synthesis of valuable ethers with complete anti-Markovnikov regioselectivity.1 Introduction2 Anti-Markovnikov Alkoxylation of Alkenes: Background3 Addition of Alkoxyl Radicals to Styrenes4 Summary and Outlook
2020 ◽
2019 ◽
Vol 84
(10)
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pp. 6475-6482
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Keyword(s):
Keyword(s):
2019 ◽
Vol 84
(11)
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pp. 6895-6903
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2018 ◽
Vol 57
(9)
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pp. 2469-2473
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Keyword(s):
2020 ◽