99mTc-Leukocyte Scintigraphy in Prosthetic Vascular Graft Infections

1989 ◽  
Vol 28 (03) ◽  
pp. 95-99 ◽  
Author(s):  
J. Laitinen ◽  
J. Lehtonen ◽  
I. Soini ◽  
I. Toivio ◽  
R. Mokka ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Graft Infection ◽  
Diagnostic Value ◽  
Late Infection ◽  
Vascular Graft Infection ◽  
Three Phase ◽  
Leukocyte Scintigraphy ◽  
99Mtc Hmpao ◽  
Prosthetic Vascular Graft Infection

The aim of this study was to determine the diagnostic value of scintigraphy with 99mTc-HMPAO-labelled leukocytes for the detection of prosthetic vascular graft infection. 51 scans were recorded in 19 patients with suspected vascular graft infection and 8 control patients. Three-phase scanning was used at 0.5, 3 – 6 and 18–24 h. 13 vascular graft infections (10 early, 3 late) were found. 12 of these healed with antibiotics and only one patient with late infection had to be reoperated. None of them died during the follow-up period. The sensitivity was 100% and the specificity 96%. 99mTc-leukocyte scintigraphy seems a useful tool to detect vascular graft infection and to differentiate it from infections elsewhere. The results suggest that the incidence of vascular graft infection may be greater, and the mortality rate lower, than supposed before.

In-vivo evaluation of the effect of cyanoacrylate on prosthetic vascular graft infection – does cyanoacrylate increase the severity of infection?

VASA ◽  
2020 ◽  
Vol 49 (4) ◽  
pp. 281-284
Author(s):  
Atıf Yolgosteren ◽  
Gencehan Kumtepe ◽  
Melda Payaslioglu ◽  
Cuneyt Ozakin
Keyword(s):  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Group 4 ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Prosthetic Vascular Graft Infection ◽  
Group 1

Summary. Background: Prosthetic vascular graft infection (PVGI) is a complication with high mortality. Cyanoacrylate (CA) is an adhesive which has been used in a number of surgical procedures. In this in-vivo study, we aimed to evaluate the relationship between PVGI and CA. Materials and methods: Thirty-two rats were equally divided into four groups. Pouch was formed on back of rats until deep fascia. In group 1, vascular graft with polyethyleneterephthalate (PET) was placed into pouch. In group 2, MRSA strain with a density of 1 ml 0.5 MacFarland was injected into pouch. In group 3, 1 cm 2 vascular graft with PET piece was placed into pouch and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. In group 4, 1 cm 2 vascular graft with PET piece impregnated with N-butyl cyanoacrylate-based adhesive was placed and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. All rats were scarified in 96th hour, culture samples were taken where intervention was performed and were evaluated microbiologically. Bacteria reproducing in each group were numerically evaluated based on colony-forming unit (CFU/ml) and compared by taking their average. Results: MRSA reproduction of 0 CFU/ml in group 1, of 1410 CFU/ml in group 2, of 180 200 CFU/ml in group 3 and of 625 300 CFU/ml in group 4 was present. A statistically significant difference was present between group 1 and group 4 (p < 0.01), between group 2 and group 4 (p < 0.01), between group 3 and group 4 (p < 0.05). In terms of reproduction, no statistically significant difference was found in group 1, group 2, group 3 in themselves. Conclusions: We observed that the rate of infection increased in the cyanoacyrylate group where cyanoacrylate was used. We think that surgeon should be more careful in using CA in vascular surgery.

Diagnosing prosthetic vascular graft infection with the antigranulocyte antibody 99mTc-fanolesomab

2007 ◽  
Vol 28 (4) ◽  
pp. 297-300 ◽  
Author(s):  
Gene G. Tronco ◽  
Charito Love ◽  
Josephine N. Rini ◽  
Alice K. Yu ◽  
Kuldeep K. Bhargava ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Prosthetic Vascular Graft Infection ◽  
Antigranulocyte Antibody

scholarly journals Tolerability of High Doses of Daptomycin in the Treatment of Prosthetic Vascular Graft Infection: A Retrospective Study

2014 ◽  
Vol 3 (2) ◽  
pp. 215-223 ◽  
Author(s):  
Laurence Legout ◽  
Piervito D’Elia ◽  
Beatrice Sarraz-Bournet ◽  
Nicolas Ettahar ◽  
Stephan Haulon ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
High Doses ◽  
Prosthetic Vascular Graft Infection

scholarly journals 2141. Characteristics and Prognosis of Patients with a Prosthetic Vascular Graft Infection (PVGI): A Prospective Cohort of 200 patients

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S630-S630
Author(s):  
Armelle Pasquet ◽  
Olivier Robineau ◽  
Michel Valette ◽  
Pier-Vito D’Elia ◽  
Sylvie Vandamme ◽  
...  
Keyword(s):  
Prospective Cohort ◽  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Prosthetic Vascular Graft Infection

scholarly journals Retrospective Study Comparing WBC scan and 18F-FDG PET/CT in Patients with Suspected Prosthetic Vascular Graft Infection

2019 ◽  
Vol 57 (6) ◽  
pp. 876-884 ◽  
Author(s):  
Mathilde Puges ◽  
Xavier Bérard ◽  
Jean-Baptiste Ruiz ◽  
Frederic Debordeaux ◽  
Arnaud Desclaux ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Fdg Pet ◽  
Vascular Graft ◽  
Graft Infection ◽  
Vascular Graft Infection ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Prosthetic Vascular Graft Infection

Management and Outcome of Prosthetic Vascular Graft Infections: A Single Center Experience

2018 ◽  
Vol 52 (3) ◽  
pp. 181-187 ◽  
Author(s):  
Maxime Elens ◽  
Muzhakkir Dusoruth ◽  
Parla Astarci ◽  
Stefano Mastrobuoni ◽  
Michel J. Bosiers ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Graft Infection ◽  
Prosthetic Graft ◽  
Long Term Results ◽  
High Morbidity ◽  
Vascular Graft Infection ◽  
Complete Excision ◽  
Single Center Experience ◽  
Initial Surgery ◽  
Prosthetic Vascular Graft Infection

Background: Prosthetic vascular graft infection (PVGI) remains a severe and challenging complication in vascular surgery with high morbidity and mortality rates. Incidence has been reported between 1% and 6%. The aim of this study was to report our experience in terms of general and surgical management as well as outcome, over 15 years. Methods: A retrospective consecutive study was conducted of all patients treated in our department for PVGI between January 2000 and December 2015. We analyzed all data relative to primary operation, duration interval between initial surgery and infections signs, infection site, type of microorganism involved, and surgical treatment modality, as well as evaluation of short- and long-term results. Results: Sixty-two patients were admitted for PVGI. Primary revascularization procedures consisted of a peripheral bypass in 42 (68%) patients and an aortic bypass in the remaining 20 (32%) patients. Median interval between primary procedure and reintervention was 3 months (interquartile range 17 [IQR 17]) in the peripheral group and 48 months (IQR 70.5) in the aortic group. Complete excision of the prosthetic graft was carried out in 85% of the cases. Thirty-day mortality was 0% and 9.5% in the aortic and peripheral group, respectively. The overall survival rate was 62.3% at 2-years, 46.4% in the aortic group, and 69.7% in the peripheral group. Conclusions: Prosthetic vascular graft infection needs a multidisciplinary management with appropriate antibiotherapy, radical removal of the infected graft, and in situ reconstruction. This strategy gives satisfactory results in terms of mortality, morbidity, patency rates, and infection control.

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