Preeclampsia: The Need for a Biological Definition and Diagnosis

2020 ◽  
Author(s):  
Alex C. Vidaeff ◽  
George R. Saade ◽  
Baha M. Sibai
Keyword(s):  
Maternal Morbidity ◽  
Early Stage ◽  
Signs And Symptoms ◽  
Morbidity And Mortality ◽  
Screening Methods ◽  
Perinatal Morbidity ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Morbidity And Mortality ◽  
Management Approaches ◽  
Clinical Continuum

AbstractThe centuries-old approach to the prevention of eclampsia and its associated maternal morbidity and mortality is based on the recognition of the presence of premonitory signs and symptoms such as hypertension and proteinuria. The spectrum of preceding signs and symptoms came to be known as preeclampsia, which is debatably considered to be an early stage on a clinical continuum possibly leading to eclampsia. The premonitory signs and symptoms were then construed as diagnostic criteria for the poorly understood syndrome of preeclampsia, and this led to a perpetual debate that remains subject to wide disagreement and periodic updates. In this commentary, we will draw attention to the fact that the criteria for preeclampsia should be viewed from the prism of a screening test rather than as diagnostic of a condition in itself. Focusing research on developing better diagnostic and screening methods for what is clinically important, namely maternal and perinatal morbidity and mortality from hypertensive disorders of pregnancy, a long overdue upgrade from what was possible centuries ago, will ultimately lead to better management approaches to what really matters.

scholarly journals Study of maternal and perinatal outcome in abruptio placentae

2020 ◽  
Vol 9 (5) ◽  
pp. 1882
Author(s):  
Krupa Patel ◽  
Jaydeep Bhatu ◽  
Swati Patel
Keyword(s):  
Perinatal Outcome ◽  
Maternal Morbidity ◽  
Placental Abruption ◽  
Placenta Previa ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Abruptio Placentae ◽  
Medical Facilities ◽  
Maternal Morbidity And Mortality ◽  
Future Management

Background: Abruptio placentae is very frequently seen in our population. Few studies have reported maternal and fetal morbidity and mortality associated with this condition. No work has been done on abruptio placentae in our setup. The data generated will help to improve maternal and fetal morbidity and mortality by planning prompt management of future cases of placental abruption. Objective of this study was to study possible etiological factors of abruptio placentae, analyse maternal outcome, perinatal outcome in the form of maternal morbidity and mortality and discuss possible preventive measures and future management optionMethods: The retrospective observational study it was included all cases presenting with ante partum haemorrhage during the study period. Subjects selected for the study were all cases diagnosed as having abruptio placentae. All other causes of APH like placenta previa and other extraplacental causes were excluded.Results: In the present study incidence of abruptio placentae is higher in 25-30 year that were 42.5% and more in 2nd gravida patient. PIH was accounting for 50%, most of the patients (95%) were anaemic at admission and majority of them required blood transfusion.one maternal mortality (2.5%) occurred, perinatal mortality was 75%.Conclusions: Abruptio placentae serious condition with manifestation of significant maternal and perinatal morbidity and mortality. Complications can be reduced by provisional antenatal care to every woman and with improvement in medical facilities, availability of blood transfusion, proper management of shock. With liberalization of caesarean section, the rate of maternal morbidity and mortality is gradually on the decline.

scholarly journals Feto-maternal outcome study in hypertensive disorders of pregnancy: primigravida vs multigravida

2021 ◽  
Vol 10 (3) ◽  
pp. 920
Author(s):  
Jaydeb Mandal ◽  
Dibyendu Roy
Keyword(s):  
Birth Weight ◽  
Maternal Morbidity ◽  
Mode Of Delivery ◽  
Perinatal Outcomes ◽  
Fetal Outcome ◽  
Morbidity And Mortality ◽  
Outcome Study ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Maternal Morbidity And Mortality

Background: Approximately 7-10% of all pregnancies are complicated by some form of hypertensive disorders. Hypertensive disorders of pregnancy (HDP) are major cause of maternal morbidity and mortality as well as fetal complications. This study is aimed to determine and compare the maternal and perinatal outcomes of hypertensive pregnancies in between primigravida and multigravida.Methods: After taking college ethical committee permission a prospective comparative study was done in our medical college from January 2017 to April 2017 with 300 women having HDP from 3658 admitted patients in that time. They were enquired and followed up as per questionnaire till their discharge from the hospital. Among study women 174 women were primigravida, 126 were multigravida. The prevalence of maternal events and complications like eclampsia, IUGR, preterm labour (PTL), HELLP syndrome DIC, mode of delivery and fetal events like Apgar’s score, birth weight were studied and compared among primigravida and multigravida. All the events related to pregnancy outcomes were analyzed statistically.Results: Our study shows prevalence of HDP was 8.2% of total admitted patients, of them 58% were primigravida, 42% multigravida. Primigravida compared to multigravida had a higher tendency to have IUGR, PTL. DIC is also slightly more in primigravida but placental abruption and PPH were more in multigravida. Fetal outcome study showed babies born with low birth weight is significantly more in primigravida and higher incidence of severe asphyxiated babies were born in primigravida. More than 40% primigravida were terminated by caesarean section, most of them had emergency indication.Conclusions: Primigravidas are more sufferer to HDP and its complications. Comprehensive antenatal care at the same time strict vigilance during delivery and quality postnatal care of high risk patients specially primigravida group could significantly reduce maternal morbidity and mortality and improves fetal outcome.

scholarly journals 639 Co-occuring opioid and methamphetamine use disorder and severe maternal morbidity and mortality in Utah

2021 ◽  
Vol 224 (2) ◽  
pp. S401-S402
Author(s):  
Marcela Smid ◽  
Amanda A. Allshouse ◽  
Kristine Campbell ◽  
Michelle P. Debbink ◽  
Adam G. Gordon ◽  
...  
Keyword(s):  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Methamphetamine Use ◽  
Maternal Morbidity And Mortality ◽  
Methamphetamine Use Disorder

scholarly journals Severe Maternal Morbidity and Mortality Among Indigenous Women in the United States

2020 ◽  
Vol 135 (2) ◽  
pp. 294-300 ◽  
Author(s):  
Katy B. Kozhimannil ◽  
Julia D. Interrante ◽  
Alena N. Tofte ◽  
Lindsay K. Admon
Keyword(s):  
United States ◽  
Maternal Morbidity ◽  
The United States ◽  
Indigenous Women ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Maternal Morbidity And Mortality

112: An international collaboration for the prevention of severe maternal morbidity and mortality

2015 ◽  
Vol 212 (1) ◽  
pp. S73-S74
Author(s):  
Steve Rad ◽  
Godfrey Mugyenyi ◽  
Gabriel Ganyaglo ◽  
Paul Sobolewski ◽  
Nathaniel Sugiyama ◽  
...  
Keyword(s):  
International Collaboration ◽  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Maternal Morbidity And Mortality

scholarly journals Maternal morbidity and mortality : an iceberg phenomenon

2021 ◽  
Author(s):  
S. Leitao ◽  
E. Manning ◽  
R. A. Greene ◽  
P. Corcoran ◽  
Bridgette Byrne ◽  
...  
Keyword(s):  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Maternal Morbidity And Mortality

scholarly journals Venomous Snakebite in Pregnancy and Good Outcome –A Case Report

2016 ◽  
Vol 27 (2) ◽  
pp. 86-88
Author(s):  
Mohammad Ali ◽  
Md Robed Amin ◽  
Mohammad Belalul Islam ◽  
Mohammad Haresur Rahman ◽  
Md Mahbubul Islam Mojumdar
Keyword(s):  
Case Report ◽  
Maternal Morbidity ◽  
Medical Literature ◽  
Morbidity And Mortality ◽  
Good Outcome ◽  
Fetal Wastage ◽  
Maternal Morbidity And Mortality ◽  
In Pregnancy

Worldwide occurrence of snakebite in pregnancy is little known in medical literature. Furthermore to the best of our knowledge there is no case report on Krait envenomation in pregnancy in Bangladesh. It carries significant fetal wastage and maternal morbidity and mortality. Here we report a mutligravida aged 27 years at her 24 weeks of gestation with krait bite with neuroparesis with good obstetrical outcome.Bangladesh J Medicine Jul 2016; 27(2) : 86-88

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