Intravascular Papillary Endothelial Hyperplasia: Case Report of a Recurrent Masson’s Tumor of the Finger and Review of Literature

Author(s):  
Hannah Jia Hui Ng ◽  
Brenton Ruiqin Sio ◽  
Vijayadwaja Desai ◽  
Kian Ming Chew ◽  
Vaikunthan Rajaratnam

AbstractIntravascular papillary endothelial hyperplasia (IPEH), often referred to as Masson’s Tumor, is an uncommon yet benign vascular disease of the skin and subcutaneous tissues. It usually arises within a blood vessel, but is considered to be a non-neoplastic reactive endothelial proliferation commonly associated with vascular injury. Although it is rare, knowledge of this disease is important as it may mimic other benign and malignant tumors, especially angiosarcoma, which may lead to unnecessary aggressive management. Typically, IPEHs are asymptomatic and are slow growing soft-tissue masses with extremely low-recurrence rates. In this article, we describe a 19-year-old male with a recurrence of Masson’s Tumor over the right little finger within 2 months of a routine excision of the lesion. We also present accompanying multimodality clinical, radiological, and pathological imaging. This case illustrates the innocuous nature of the initial lesion easily mistaken for a hemangioma. Awareness of the possibility of a recurrence of a Masson’s Tumor is important for clinicians to rule out the presence of malignant vascular lesions.

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Parviz Mardani ◽  
Amir Askari ◽  
Reza Shahriarirad ◽  
Keivan Ranjbar ◽  
Amirhossein Erfani ◽  
...  

Masson’s tumor or Masson’s hemangioma, more precisely termed intravascular papillary endothelial hyperplasia (IPEH), is an uncommon benign vascular lesion of the skin and subcutaneous tissues which can be frequently confused with angiosarcoma. Although relatively rare, its accurate diagnosis is essential since it can clinically be similar to both benign and malignant lesions. We present a 39-year-old man with a round bulging arising from the left palm side of the hand with gradual growth in the last 5 months and on and off tenderness. The microscopic section demonstrated the papillary proliferation of endothelial cells in favor of Masson’s hemangioma, which was sufficiently treated with excision alone.


2020 ◽  
Vol 63 (11) ◽  
pp. 541-544
Author(s):  
Hoyoung Lee ◽  
Soo Jeong Choi ◽  
In Hak Choi ◽  
Kwang Yoon Jung

Masson’s tumor, also known as intravascular papillary endothelial hyperplasia (IPEH), is a rare, benign vascular tumor characterized by the proliferation of endothelial cells with papillary formations. Differential diagnosis between IPEH and angiosarcoma is important because both have microscopic similarity. Herein, we report a rare case of IPEH on the right lateral neck of a 50-year-old female presenting with a neck mass, which was completely removed without complication.


2010 ◽  
Vol 2 (1) ◽  
pp. 22-26 ◽  
Author(s):  
Ronell Bologna-Molina ◽  
Guillermo Amezcua-Rosas ◽  
Israel Guardado-Luevanos ◽  
Patricia Lorelei Mendoza-Roaf ◽  
Tomás González-Montemayor ◽  
...  

2015 ◽  
Vol 15 (4) ◽  
pp. 384-391 ◽  
Author(s):  
Sook Young Sim ◽  
Yong Cheol Lim ◽  
Keun Soo Won ◽  
Kyung Gi Cho

Intracranial intravascular papillary endothelial hyperplasia (IPEH) is very rare, and to our knowledge long-term follow-up results have not been previously published. An 11-year-old boy presented with a 6-month history of progressive visual impairment in the right eye. Magnetic resonance imaging revealed a well-enhanced, large parasellar mass involving the cavernous sinus, right frontal skull base, and ethmoid and sphenoid sinuses. Frontotemporal craniotomy and subtotal resection were performed, and the diagnosis of IPEH was confirmed. The mass increased in size during the following 3 months. A second operation was performed via frontotemporal craniotomy combined with a transsphenoidal approach, and gross-total resection of the tumor was achieved. Adjuvant radiotherapy (5040 cGy) and chemotherapy with interferon were administered. The patient's visual symptoms improved, and there was no recurrence during a 13-year follow-up period. The results of this case indicate that intracranial IPEH can recur with subtotal resection; however, optimal resection with multimodal adjuvant treatment can control the disease for many years, if not permanently.


2018 ◽  
Vol 128 (6) ◽  
pp. 1725-1730 ◽  
Author(s):  
Lefko T. Charalambous ◽  
Anirudh Penumaka ◽  
Jordan M. Komisarow ◽  
Amanda C. Hemmerich ◽  
Thomas J. Cummings ◽  
...  

Intracranial intravascular papillary endothelial hyperplasia (IPEH), also referred to as Masson’s tumor, is a condition that rarely occurs in the nervous system. IPEH most frequently occurs extracranially in the skin of the face, skull, neck, and trunk and can easily be mistaken clinically, radiologically, and histologically for angiosarcoma, organizing hematoma, or other vascular malformations. IPEH accounts for roughly 2% of all vascular tumors and is extremely rare intracranially, with only 23 reported cases compared with more than 300 cases of IPEH occurring in the skin and subcutaneous tissue. To date, it has never been reported to occur in the pineal region. The authors report the case of a patient with an IPEH in the pineal region who underwent complex resection and experienced reversal of neurological symptoms.


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