scholarly journals A CASE OF DISSEMINATED TUBERCULOSIS WITH OCULAR INVOLVEMENT

2015 ◽  
Vol 05 (01) ◽  
pp. 094-096
Author(s):  
Md Fekarul Islam ◽  
Devdeep Mukherjee ◽  
Ritabrata Kundu ◽  
Prabal Chandra Niyogi ◽  
Joydeep Das
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Corneal Opacity ◽  
Ocular Involvement ◽  
Disseminated Tuberculosis ◽  
Ocular Manifestations ◽  
The Central Nervous System ◽  
Immunocompromised State ◽  
Ocular Tb ◽  
Posterior Synechiae

AbstractDisseminated Tuberculosis (DTB) refers to tubercular involvement of two or more non-contiguous sites and is commonly associated with immunocompromised state. It is an unusual presentation of Tuberculosis (TB), especially in the absence of immunodeficiency. 1.4% of patients with Pulmonary Tuberculosis (PTB) develop ocular manifestations but many patients with ocular TB have no evidence of PTB. Tuberculosis can cause a wide variety of ophthalmic findings, ranging from the ocular surface through the optic nerve and to the central nervous system. In this article, we report a case of Disseminated Tuberculosis with ocular involvement in a 5years old female. Our case is unique for the presence of bilateral squint, unilateral nebular type of corneal opacity, bilateral iritis with posterior synechiae and cataract at the same time. It lays emphasis on the fact that a patient with tuberculosis should be screened for multiple foci.

scholarly journals Multiple Sclerosis Revealed by Anterior Uveitis

2020 ◽  
Vol 2 (5) ◽  
Author(s):  
Sidi Dahi ◽  
Mehdi Khamaily ◽  
Joumany Brahim Salem ◽  
Imane Tarib ◽  
Mounia Bouchaar ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Inflammatory Disease ◽  
Anterior Uveitis ◽  
Oculomotor Nerve ◽  
Ocular Involvement ◽  
Atypical Case ◽  
Autoimmune Inflammatory Disease ◽  
The Central Nervous System

Multiple sclerosis is an autoimmune inflammatory disease of the central nervous system, leading to the formation of foci of demyelination. Ocular involvement is quite frequent and multiple, dominated by inflammatory optic neuropathies, oculomotor nerve damage, nystagmus and uveitis. We report an atypical case of multiple sclerosis revealed by an anterior unilateral synechiatic hypertensive uveitis in a young patient of 27 years.

Disseminated tuberculosis of the central nervous system responsive to rifabutin

1990 ◽  
Vol 11 (2) ◽  
pp. 163-169 ◽  
Author(s):  
M. Riva ◽  
S. Crippa ◽  
F. Di Palma ◽  
A. M. Gerini ◽  
E. Soresi ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Disseminated Tuberculosis ◽  
The Central Nervous System

scholarly journals A Rare Presentation of Invasive Tuberculosis of the Central Nervous System in an Immunocompetent Patient in a Nonendemic Country

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Rita Martins ◽  
Carlos Casimiro ◽  
Ana Valverde ◽  
Jose Campillo
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Immunocompetent Patient ◽  
Cerebral Lesions ◽  
Rare Presentation ◽  
Disseminated Tuberculosis ◽  
Meningeal Involvement ◽  
Susceptibility Factors ◽  
The Central Nervous System ◽  
High Index Of Suspicion

We herein report a rare case of a 25-year-old immunocompetent male patient with disseminated tuberculosis of central nervous system (CNS), first presenting as multiple cerebral lesions with no meningeal involvement. Subsequent diagnostic workup disclosed extensive peritoneal involvement. A broad differential diagnosis was considered, including neoplastic and infectious diseases. The diagnosis was confirmed with positive PCR result for Mycobacterium tuberculosis in the biopsied mesenteric tissue. The patient was started on tuberculostatic regimen with favorable outcome. No acquired or hereditary immunodeficiency was documented. Disseminated tuberculosis in immunocompetent individuals is extremely rare. Genetic susceptibility factors have been reported in individuals with extensive forms of the disease and a high index of suspicion is required, as observed in our case.

Effects of Hyperoxia on Lung Utrastructure

1970 ◽  
Vol 28 ◽  
pp. 26-27
Author(s):  
Gladys Harrison
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Light Microscopy ◽  
Oxygen Effects ◽  
Age Dependent ◽  
The Central Nervous System ◽  
The Subject ◽  
Space Age ◽  
Alveolar Septa ◽  
Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

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