Formal Synthesis of (±)-Aplykurodinone-1 Based on the Indium-Catalyzed Conia-Ene Reaction
Keyword(s):
A concise formal synthesis of (±)-aplykurodinone-1 starting from a commercially available material and based on the indium-catalyzed Conia-ene reaction has been accomplished. The synthesis features a Riley selenium dioxide oxidation, a Krapcho dealkoxycarbonylation, and a ring-closing metathesis approach. The synthetic strategy was also supported by a Saegusa oxidation and a classic Michael 1,4-conjugate addition.
2015 ◽
Vol 11
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pp. 1514-1519
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Keyword(s):
2005 ◽
Vol 46
(37)
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pp. 6257-6259
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2002 ◽
Vol 43
(2)
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pp. 295-298
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