scholarly journals One-Pot Synthesis of Cycloparaphenylenes

2020 ◽  
Vol 02 (04) ◽  
pp. 306-312
Author(s):  
Jan H. Griwatz ◽  
Hermann A. Wegner
Keyword(s):  
Transition Metal ◽  
Organic Synthesis ◽  
Organic Materials ◽  
Selective Synthesis ◽  
Coupling Reactions ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
One Pot Synthesis

The preparation of cycloparaphenylenes ([n]CPPs) with their bent π-system poses a long-standing challenge in organic synthesis. In the current multi-step approaches to access CPPs, pre-angulated precursors were combined using transition metal-catalysed or mediated coupling reactions. Therefore, there is a long way to the realisation of the idea of an ‘ideal synthesis’. An easy and efficient synthesis of different [n]CPPs would represent a breakthrough, also pushing their incorporation into organic materials. By combining multiple steps in a one-pot approach, the overall time and workload can be drastically shortened. Herein, we present the application of this concept for the preparation of [6] and [9]CPP as a simple and fast alternative to current methods. By tuning the reaction conditions the selective synthesis of both [6] and [9]CPP was demonstrated.

A one-pot synthesis of 2,2′-disubstituted diindolylmethanes (DIMs) via a sequential Sonogashira coupling and cycloisomerization/C3-functionalization of 2-iodoanilines

2017 ◽  
Vol 15 (33) ◽  
pp. 6997-7007 ◽  
Author(s):  
Anirban Kayet ◽  
Vinod K. Singh
Keyword(s):  
Sonogashira Coupling ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis

Pd(ii)–Ag(i) catalysed, highly efficient synthesis of diindolylmethanes under mild reaction conditions, with six new bonds being formed in a one-pot fashion, and the products being transformed into synthetically useful compounds.

Structure and Conformational Properties of three-layered Cyclophanes prepared by a one-pot Synthesis

2007 ◽  
Vol 2007 (7) ◽  
pp. 429-431
Author(s):  
Akihiko Tsuge ◽  
Takahiro Okamoto ◽  
Tetsuji Moriguch
Keyword(s):  
Coupling Reactions ◽  
Benzene Derivatives ◽  
Reaction Conditions ◽  
One Pot ◽  
Conformational Isomers ◽  
One Pot Synthesis ◽  
Conformational Properties

The coupling reactions of substituted bis(bromomethyl)benzene components and tetra(mercaptomethyl)benzene derivatives have been carried out under heterogeneous dilute reaction conditions to afford the three-layered cyclophanes 3a–e as three kinds of conformational isomers in moderate yields.

scholarly journals Sequential decarboxylative azide–alkyne cycloaddition and dehydrogenative coupling reactions: one-pot synthesis of polycyclic fused triazoles

2014 ◽  
Vol 10 ◽  
pp. 3031-3037 ◽  
Author(s):  
Kuppusamy Bharathimohan ◽  
Thanasekaran Ponpandian ◽  
A Jafar Ahamed ◽  
Nattamai Bhuvanesh
Keyword(s):  
Transition Metal ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
One Pot ◽  
Triazole Derivatives ◽  
One Pot Synthesis ◽  
Cross Coupling Reactions ◽  
Dehydrogenative Coupling ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Herein, we describe a one-pot protocol for the synthesis of a novel series of polycyclic triazole derivatives. Transition metal-catalyzed decarboxylative CuAAC and dehydrogenative cross coupling reactions are combined in a single flask and achieved good yields of the respective triazoles (up to 97% yield). This methodology is more convenient to produce the complex polycyclic molecules in a simple way.

One-pot Synthesis of Novel 2-(Benzofuran-2-yl)-4-Phenylquinoline-3-Carboxylates

2017 ◽  
Vol 41 (1) ◽  
pp. 45-49
Author(s):  
Wentao Gao ◽  
Xinbo Fu ◽  
Yanan Zhao ◽  
Dongfang Wang
Keyword(s):  
Transition Metal ◽  
Efficient Synthesis ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis ◽  
The One

A facile and efficient synthesis of novel ethyl 2-(benzofuran-2-yl)-4-phenylquinoline-3-carboxylates and the corresponding acids through the one-pot three-step reaction of ethyl 2-(chloromethyl)-4-phenylquinoline-3-carboxylate with a series of salicylaldehydes is described. It allows an efficient and practical access to some 2-(benzofuran-2-yl)quinolines under transition-metal-free conditions.

scholarly journals One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Catalyzed by Chlorosulfonic Acid

2005 ◽  
Vol 2 (4) ◽  
pp. 228-230 ◽  
Author(s):  
Jin Tong-Shou ◽  
Zhao Ying ◽  
Liu Li-Bin ◽  
Li Tong-Shuang
Keyword(s):  
Reaction Time ◽  
Biginelli Reaction ◽  
Chlorosulfonic Acid ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Short Reaction Time ◽  
One Pot Synthesis

An efficient synthesis of 3,4-dihydropyrimidin-2-ones (DHPMs) from the aldehydes, β-ketoesters and urea in ethanol using chlorosulfonic acid as the catalyst is described. Compared with the classical Biginelli reaction conditions, this method has the advantage of excellent yields and short reaction time.

Samarium Chloride Catalysed Biginelli Reaction: One-Pot synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones

2002 ◽  
Vol 2002 (9) ◽  
pp. 436-438 ◽  
Author(s):  
Xuesen Fan ◽  
Xinying Zhang ◽  
Yongmin Zhang
Keyword(s):  
Biginelli Reaction ◽  
New Method ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Keto Ester ◽  
One Pot Synthesis ◽  
Samarium Chloride

An efficient synthesis of 3,4-dihydropyrimidin-2(1 H)-one derivatives using samarium chloride as a catalyst from aldehyde, β-keto ester and urea or thiourea in ethanol is described; compared to the classical Biginelli method, this new method has the advantages of good yields and milder reaction conditions.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

Synthesis of pyrazolo[1,5-c]quinazoline derivatives through the copper-catalyzed domino reaction of o-alkenyl aromatic isocyanides with diazo compounds

2020 ◽  
Vol 56 (55) ◽  
pp. 7665-7668 ◽  
Author(s):  
Lu Liu ◽  
Lei Li ◽  
Shukuan Mao ◽  
Xin Wang ◽  
Ming-Dong Zhou ◽  
...  
Keyword(s):  
Diazo Compounds ◽  
Domino Reaction ◽  
Reaction Conditions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

Various o-alkenyl aromatic isocyanides were prepared from readily available reactants for their double annulation with diazo compounds for a one-pot synthesis of pyrazolo[1,5-c]quinazolines under mild reaction conditions.

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